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首页> 外文期刊>Gastrointestinal Endoscopy >Wireless capsule endoscopy and portal hypertensive intestinal vasculopathy.
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Wireless capsule endoscopy and portal hypertensive intestinal vasculopathy.

机译：无线胶囊内窥镜检查和门脉高压性肠血管病。

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摘要

Bleeding from complications of portal hypertension is associated with significant morbidity and mortality. Increased resistance to portal-blood flow is the primary factor in cirrhosis, which leads to portal hypertension. However, in addition to the increased resistance at the prehepatic, intrahepatic, or posthepatic level, there is an increase in portal venous inflow that maintains and exacerbates portal hypertension. This increased portal venous inflow is the result of marked arteriolar dilation in the splanchnic organs draining into the portal vein. These vascular changes are mediated, in part, by imbalances in vasoconstrictors and vasodilators at both the liver and the splanchnic circulation. These factors contribute to the portal hypertensive syndrome, resulting in the spectrum of gastropathy, enteropathy,and colopathy. During the past decades, overt GI bleeding and anemia secondary to chronic blood loss from portal hypertensive gastropathy (PHG) and other sites of the intestinal mucosa, including the small bowel and the colon, have been described, thus leading to the term of portal hypertensive intestinal vasculopathy (PHIV), which embraces the effects of portal hypertension on the entire bowel and includes portal gastropathy, enteropathy and colopathy.
机译：门静脉高压症并发症引起的出血与明显的发病率和死亡率有关。对门静脉血流的抵抗力增加是肝硬化的主要因素，这会导致门脉高压。但是，除了在肝前，肝内或肝后水平上增加的抵抗力之外，门静脉流入量的增加也维持并加重了门静脉高压。这种增加的门静脉流入是内脏器官显着的小动脉扩张流入门静脉的结果。这些血管变化部分是由肝脏和内脏循环处的血管收缩剂和血管扩张剂的失衡所介导的。这些因素导致门脉高压症候群，导致胃病，肠病和结肠病的发生。在过去的几十年中，已经描述了由于门脉高压性胃病（PHG）和肠粘膜其他部位（包括小肠和结肠）而导致的慢性失血引起的明显的胃肠道出血和贫血，因此被称为门脉高压肠道血管病（PHIV），包括门脉高压对整个肠的影响，包括门脉胃病，肠病和结肠病。

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