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Diagnosis of elevated-type early gastric cancers by the optimal band imaging system.

机译：通过最佳波段成像系统诊断升高型早期胃癌。

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BACKGROUND: The endoscopic diagnosis of an elevated-type early gastric cancer is often difficult. The optimal band imaging (OBI) system can reconstruct the best spectral images decomposed from ordinary endoscopic images with free selection of 3 wavelengths and provide unmagnified images with high light intensity as well as magnified images. OBJECTIVE: To evaluate whether the OBI system facilitates detection of the demarcation lines between an elevated-type early gastric cancer and surrounding tissue and thus is more helpful for performing endoscopic therapy. DESIGN: A prospective study. SETTING: Jichi Medical University, Japan. PATIENTS: Seventy-five patients, 81 lesions with an elevated-type early gastric cancer. MAIN OUTCOME MEASUREMENTS: A comparison between OBI images and conventional endoscopic images in the identification of the demarcation lines of an elevated-type early gastric cancer without magnification and the rate of success in identifying the abnormal surface structure of cancer by using low-magnified OBI images. RESULTS: Demarcation lines were easily identified in OBI images, even without magnification, because such cancers could be clearly distinguished from the surrounding whitish atrophic mucosa. Inexperienced endoscopists could determine demarcation lines with significantly greater accuracy with unmagnified OBI images than with conventional images. With 40-fold magnification, irregular microstructural or nonstructural patterns were also found within cancer lesions in all cases studied but in none of the cases in the surrounding noncancerous mucosa. CONCLUSIONS: The new contrast images obtained with the OBI system enable better determination of the demarcation lines of elevated-type early gastric cancers, and this system may be useful for performing endoscopic therapy of this type of cancer as a new endoscopic modality.
机译：背景：内镜诊断升高型早期胃癌通常很困难。最佳波段成像（OBI）系统可以自由选择3种波长来重建从普通内窥镜图像分解而来的最佳光谱图像，并提供具有高光强度的未放大图像和放大图像。目的：评估OBI系统是否有助于检测高架型早期胃癌和周围组织之间的分界线，从而对进行内窥镜治疗更有帮助。设计：一项前瞻性研究。地点：日本吉知医科大学。患者：75例患者，其中81例为早期胃癌高发型病变。主要观察指标：OBI图像与常规内窥镜图像之间的比较，用于在不放大的情况下识别高架型早期胃癌的分界线，以及使用低倍率OBI图像识别癌症异常表面结构的成功率。结果：即使在没有放大的情况下，OBI图像也很容易识别分界线，因为可以将这种癌症与周围的白色萎缩性粘膜区分开来。没有经验的内窥镜检查者可以使用未放大的OBI图像确定分界线，其准确性要比传统图像高得多。放大40倍，在所有研究的病例中，在癌病灶中也发现了不规则的微结构或非结构性模式，但在周围的非癌性粘膜中都没有发现。结论：OBI系统获得的新的对比图像能够更好地确定高架型早期胃癌的分界线，并且该系统对于作为新的内窥镜形式对这种类型的癌症进行内窥镜治疗可能是有用的。

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