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Diagnostic accuracy of the mood module of the Patient Health Questionnaire: a systematic review.

机译:患者健康问卷的情绪模块的诊断准确性:系统评价。

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OBJECTIVE: The nine-item mood module of the Patient Health Questionnaire (PHQ-9) was developed to screen and to diagnose patients in primary care with depressive disorders. We systematically reviewed the psychometric literature on the PHQ-9 and performed a meta-analysis to ascertain its summary sensitivity and specificity. METHODS: EMBASE, PubMed and PsycINFO were used to search literature up to July 2006. Studies were included if (1) they investigated the diagnostic accuracy of the PHQ-9 and (2) the PHQ-9 had been compared with a reference test. The quality of the studies was appraised using the Quality Assessment of Diagnostic Accuracy Studies. We calculated sensitivity, specificity and confidence intervals for each included study. We used the random effects model to calculate the summary sensitivity and specificity. RESULTS: We found a sensitivity of 0.77 (0.71-0.84) and a specificity of 0.94 (0.90-0.97) for the PHQ-9. The positive predictive value in an unselected primary care population was 59%, which increased to 85-90% when the prior probability increased to 30-40%. CONCLUSION: In primary care, the PHQ-9 is a valid diagnostic tool if used in selected subgroups of patients with a high prevalence of depressive disorder.
机译:目的:开发了《患者健康调查表》(PHQ-9)的9个项目的情绪模块,以筛查和诊断患有抑郁症的初级保健患者。我们系统地回顾了关于PHQ-9的心理计量学文献,并进行了荟萃分析,以确定其简要的敏感性和特异性。方法:使用EMBASE,PubMed和PsycINFO检索截至2006年7月的文献。研究是否包括以下内容:(1)他们调查了PHQ-9的诊断准确性,以及(2)将PHQ-9与参考测试进行了比较。使用诊断准确性研究的质量评估对研究的质量进行评估。我们计算了每个纳入研究的敏感性,特异性和置信区间。我们使用随机效应模型来计算汇总敏感性和特异性。结果:我们发现PHQ-9的灵敏度为0.77(0.71-0.84),特异性为0.94(0.90-0.97)。未选择的初级保健人群的阳性预测值为59%,当先验概率增加到30-40%时,阳性预测值增加到85-90%。结论:在初级保健中,PHQ-9如果用于抑郁症患病率较高的部分患者亚组中,则是一种有效的诊断工具。

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