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首页> 外文期刊>Evidence-based dentistry >Lack of reliable evidence of the effectiveness of remineralising agents for the treatment of post orthodontic white spot lesions
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Lack of reliable evidence of the effectiveness of remineralising agents for the treatment of post orthodontic white spot lesions

机译：缺乏再矿化剂治疗正畸后白斑病变有效性的可靠证据

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Data sources PubMed, Medline, Web of Science and the Cochrane Library databases were searched. Study selection Selection was conducted independently by two reviewers, only randomised controlled trials were included. Study quality was assessed using the Cochrane risk of bias approach. Data extraction and synthesis Data abstraction was carried out independently by two reviewers and qualitative summary presented, because of the heterogeneity of the interventions and outcome measures. Results Seven studies were included, all except one (of medium risk) were considered to be at high risk of bias. Three studies evaluated fluoride preparations (50-ppm sodium fluoride mouth rinse, 5% sodium fluoride varnish and 0.5% sodium fluoride chewing sticks). Four compared remineralising agents containing casein phosphopeptide amorphous calcium phosphate or casein phosphopeptide amorphous calcium fluoride phosphate.
机译：检索了数据来源PubMed，Medline，Web of Science和Cochrane图书馆数据库。研究选择选择是由两名评价者独立进行的，仅包括随机对照试验。使用Cochrane偏倚风险方法评估研究质量。数据提取和综合由于干预措施和结果指标的异质性，数据摘要由两名审核员独立进行，并给出了定性摘要。结果共纳入7项研究，除一项（中等风险）外，所有其他研究均被视为有偏见的高风险。三项研究评估了氟化物制剂（50 ppm氟化钠漱口水，5％氟化钠清漆和0.5％氟化钠咀嚼棒）。比较了四种含有钙酪蛋白磷酸肽无定形磷酸钙或酪蛋白磷酸肽无定形磷酸钙的再矿化剂。

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