Current clinical evidence for the use of mesenchymal stem cells in articular cartilage repair

Reissis Dimitris; Quen Oak Tang; Cooper Nina Catherine; Carasco Clare Francesca; Gamie Zakareya; Mantalaris Athanasios; Tsiridis Eleftherios

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Current clinical evidence for the use of mesenchymal stem cells in articular cartilage repair

机译：间充质干细胞在关节软骨修复中的应用的最新临床证据

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Introduction: Articular cartilage is renowned for its poor intrinsic capacity for repair. Current treatments for osteoarthritis are limited in their ability to reliably restore the native articular cartilage structure and function. Mesenchymal stem cells (MSCs) present an attractive treatment option for articular cartilage repair, with a recent expansion of clinical trials investigating their use in patients.

机译：简介：关节软骨因其固有的修复能力差而闻名。骨关节炎的当前治疗在可靠地恢复天然关节软骨结构和功能的能力方面受到限制。间充质干细胞（MSCs）为关节软骨修复提供了一种有吸引力的治疗选择，最近一项临床试验研究了其在患者中的用途，目前正在扩大。

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《Expert opinion on biological therapy》 |2016年第4期|共23页
作者
Reissis Dimitris; Quen Oak Tang; Cooper Nina Catherine; Carasco Clare Francesca; Gamie Zakareya; Mantalaris Athanasios; Tsiridis Eleftherios;
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正文语种 eng
中图分类治疗学;
关键词
articular cartilage defects; osteoarthritis; cartilage; regeneration; Mesenchymal stem cells;

机译：关节软骨缺损;骨关节炎;软骨;再生;间充质干细胞;

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1. Current clinical evidence for the use of mesenchymal stem cells in articular cartilage repair [J] . Reissis Dimitris, Quen Oak Tang, Cooper Nina Catherine, Expert opinion on biological therapy . 2016,第4期

机译：间充质干细胞在关节软骨修复中的应用的最新临床证据
2. Adipose-Derived Mesenchymal Stem Cells for the Treatment of Articular Cartilage: A Systematic Review on Preclinical and Clinical Evidence [J] . FrancescoPerdisa, NataliaGostyńska, AliceRoffi, Stem cells international . 2015,第3期

机译：脂肪间充质干细胞治疗关节软骨：临床前和临床证据的系统评价
3. Adipose-Derived Mesenchymal Stem Cells for the Treatment of Articular Cartilage: A Systematic Review on Preclinical and Clinical Evidence [J] . Perdisa Francesco, Gostynska Natalia, Roffi Alice, Stem cells international . 2015,第3期

机译：用于治疗关节软骨的脂肪衍生的间充质干细胞：对临床前和临床证据进行系统综述
4. Collagen Type Ⅰ and Ⅱ Blend Hydrogels with Mesenchymal Stem Cells as a Scaffold for Articular Cartilage Defect Repair [C] . Claire Kilmer, Abigail Durkes, Gert J. Breur, Society for Biomaterials annual meeting and exposition . 2019

机译：Ⅰ型和Ⅱ型胶原蛋白混合水凝胶与间充质干细胞作为支架修复关节软骨缺损
5. The role of cultured chondrocytes and mesenchymal stem cells in the repair of acute articular cartilage injuries. [D] . Secretan, Charles Coleman. 2010

机译：培养的软骨细胞和间充质干细胞在修复急性关节软骨损伤中的作用。
6. Injectable Systems for Intra-Articular Delivery of Mesenchymal Stromal Cells for Cartilage Treatment: A Systematic Review of Preclinical and Clinical Evidence [O] . Alice Roffi, Norimasa Nakamura, Mikel Sanchez, 2018

机译：关节内间充质基质细胞软骨内治疗的可注射系统：临床前和临床证据的系统评价
7. Mesenchymal Stem Cells and Articular Cartilage Repair: Clinical Studies and Future Direction [O] . Punwar, Shahid, Khan, Wasim S 2011

机译：间充质干细胞和关节软骨修复：临床研究和未来方向。

Current clinical evidence for the use of mesenchymal stem cells in articular cartilage repair

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