Activating the innate immune response to counter chronic hepatitis B virus infection

Lamb Camilla; Arbuthnot Patrick

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Activating the innate immune response to counter chronic hepatitis B virus infection

机译：激活先天免疫反应以抵抗慢性乙型肝炎病毒感染

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Introduction: Chronic infection with hepatitis B virus (HBV) is endemic to several populous parts of the world, where resulting complicating cirrhosis and hepatocellular carcinoma occur commonly. Licensed drugs to treat the infection have limited curative efficacy, and development of therapies that eliminate all replication intermediates of HBV is a priority.

机译：简介：乙型肝炎病毒（HBV）的慢性感染是世界上几个人口大区的地方性流行，由此导致的复杂性肝硬化和肝细胞癌通常发生。许可用于治疗感染的药物的疗效有限，因此优先开发消除所有HBV复制中间体的疗法。

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《Expert opinion on biological therapy》 |2016年第12期|共11页
作者
Lamb Camilla; Arbuthnot Patrick;
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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
Cccdna; cytokines; HBV; immunotherapy; interferon; Toll like receptor;

机译：ccdna;细胞因子;HBV;免疫治疗;干扰素;Toll样受体;

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专利

1. Activating the innate immune response to counter chronic hepatitis B virus infection [J] . Lamb Camilla, Arbuthnot Patrick Expert opinion on biological therapy . 2016,第12期

机译：激活先天免疫反应以抵抗慢性乙型肝炎病毒感染
2. Innate and adaptive immune responses in chronic hepatitis B virus infections: Towards restoration of immune control of viral infection [J] . BertolettiA., FerrariC. Gut: Journal of the British Society of Gastroenterology . 2012,第12期

机译：慢性乙型肝炎病毒感染的先天性和适应性免疫反应：致力于恢复对病毒感染的免疫控制
3. Innate immune responses during acute and chronic hepatitis C virus infections [J] . Heim Markus Cytokine . 2015,第1期

机译：急性和慢性丙型肝炎病毒感染期间的先天免疫反应
4. Dynamics of a Chronic Hepatitis B Virus Infection Model with Drug Therapy and Immune Responses [C] . Jianhua Pang, Jing-an Cui, Jing Hui International congress on mathematical biology;ICMB2011 . 2011

机译：具有药物治疗和免疫反应的慢性乙型肝炎病毒感染模型的动力学。
5. Cause and effect: Hepatitis C virus infection and host innate immune response. [D] . Kohlway, Andrew Scott. 2013

机译：因果：丙型肝炎病毒感染和宿主固有免疫反应。
6. Saturated Fatty Acid Inhibits Viral Replication in Chronic Hepatitis B Virus Infection With Nonalcoholic Fatty Liver Disease by Toll-Like Receptor 4-Mediated Innate Immune Response [O] . Rui-Nan Zhang, Qin Pan, Zheng Zhang, 2015

机译：饱和脂肪酸抑制由Toll样受体4介导的先天免疫反应在慢性乙型肝炎病毒感染非酒精性脂肪肝疾病中的病毒复制。
7. Innate and Adaptive Immune Responses in Chronic Hepatitis C Virus and Hepatitis B Virus Infection with High Viral Loads [O] . Yutaka Kishida 2019

机译：慢性丙型肝炎病毒和乙型肝炎病毒感染的先天和适应性免疫应答高病毒载荷

Activating the innate immune response to counter chronic hepatitis B virus infection

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