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Twinrix vaccination schedules among injecting drug users.

机译:注射吸毒者中的Twinrix疫苗接种时间表。

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Twinrix is the only licensed vaccine that provides dual protection against infection with hepatitis A virus (HAV) and hepatitis B virus (HBV). The standard vaccination schedule for Twinrix is 0, 1 and 6 months. However, many high-risk populations, such as injecting drug users (IDUs), do not complete the vaccination series and, thus, do not acquire sufficient immunity against HAV and HBV. Twinrix can be administered using an accelerated vaccination schedule of 0, 7 and 21 days, with a booster recommended at 12 months. This manuscript reviews the available literature on vaccinating IDUs against HAV and HBV. The authors conclude that there is insufficient evidence regarding whether the accelerated Twinrix HAV/HBV vaccination schedule would yield a greater number of IDUs protected against both HAV and HBV.
机译:Twinrix是唯一提供双重保护的双抗疫苗,可预防甲型肝炎病毒(HAV)和乙型肝炎病毒(HBV)的感染。 Twinrix的标准疫苗接种时间表为0、1和6个月。但是,许多高危人群,例如注射吸毒者(IDU),并未完成疫苗接种系列,因此无法获得足够的抗HAV和HBV免疫力。 Twinrix可以使用0、7和21天的加速疫苗接种时间表进行管理,建议在12个月时加强接种。本手稿回顾了有关注射抗I型肝炎病毒和乙型肝炎疫苗的文献。作者得出的结论是,关于加速Twinrix HAV / HBV疫苗接种计划是否会产生更多的针对HAV和HBV的IDU,没有足够的证据。

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