PEGylated IFH beta-1a in the treatment of multiple sclerosis

Khan Umair Tahir; Tanasescu Radu; Constantinescu Cris S.

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PEGylated IFH beta-1a in the treatment of multiple sclerosis

机译：聚乙二醇化IFH beta-1a在多发性硬化症的治疗中

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Introduction: Multiple sclerosis (MS) is a chronic immune-mediated disease of the CNS characterized in most cases by a relapsing and remitting disease course, often followed by a progressive course. There are many available injectable therapies for the relapsing-remitting form of MS (RRMS); however, efficacy can be affected by poor adherence and compliance, and an increased frequency of side effects as a result of frequent injections is seen.

机译：简介：多发性硬化症（MS）是中枢神经系统的一种慢性免疫介导的疾病，在大多数情况下，其特征是疾病的复发和缓解，通常随后是进行性疾病。对于复发-缓解型MS（RRMS），有许多可用的注射疗法。然而，不良的依从性和依从性可能会影响疗效，并且经常注射会导致副作用增加。

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《Expert opinion on biological therapy》 |2015年第7期|共8页
作者
Khan Umair Tahir; Tanasescu Radu; Constantinescu Cris S.;
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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
drug evaluation; IFN; multiple sclerosis; PEGIFN beta-1aPEGylated; relapse-remitting multiple sclerosis; review;

机译：药物评价干扰素多发性硬化PEGIFN beta-1aPEG化复发缓解型多发性硬化综述;

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1. PEGylated IFH beta-1a in the treatment of multiple sclerosis [J] . Khan Umair Tahir, Tanasescu Radu, Constantinescu Cris S. Expert opinion on biological therapy . 2015,第7期

机译：聚乙二醇化IFH beta-1a在多发性硬化症的治疗中
2. PEGylated interferon beta-1a in the treatment of multiple sclerosis – an update [J] . Reinhard Reuss Biologics: Targets and Therapy . 2013,第6期

机译：聚乙二醇干扰素β-1a在多发性硬化症治疗中的应用
3. PEGylated interferon beta-1a: meeting an unmet medical need in the treatment of relapsing multiple sclerosis. [J] . Baker DP, Pepinsky RB, Brickelmaier M, Journal of interferon and cytokine research: The official journal of the International Society for Interferon and Cytokine Research . 2010,第10期

机译：聚乙二醇化干扰素β-1a：在复发性多发性硬化症的治疗中满足未满足的医学需求。
4. Agent based modeling of relapsing multiple sclerosis: a possible approach to predict treatment outcome [C] . Francesco Pappalardo, Giulia Russo, Marzio Pennisi, IEEE International Conference on Bioinformatics and Biomedicine . 2018

机译：基于Agent的复发性多发性硬化症建模：预测治疗结果的可能方法
5. Imaging Informatics-Based Electronic Patient Record and Analysis System for Multiple Sclerosis Research, Treatment, and Disease Tracking [D] . Ma, Kevin C. 2018

机译：基于信息学的电子患者记录和分析系统，用于多发性硬化研究，治疗和疾病跟踪
6. PEGylated interferon beta-1a in the treatment of multiple sclerosis – an update [O] . Reinhard Reuss 2013

机译：聚乙二醇化干扰素β-1a在多发性硬化症治疗中的应用
7. A Network Meta-Analysis of Efficacy and Evaluation of Safety of Subcutaneous Pegylated Interferon Beta-1a versus Other Injectable Therapies for the Treatment of Relapsing-Remitting Multiple Sclerosis. [O] . Keith Tolley, Michael Hutchinson, Xiaojun You, 2015

机译：皮下聚乙二醇化干扰素β-1a与其他可注射疗法治疗复发缓解型多发性硬化症的疗效和安全性评价的网络meta分析。

PEGylated IFH beta-1a in the treatment of multiple sclerosis

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