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Supramolecular approaches to biological therapy.

机译：生物疗法的超分子方法。

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摘要

Supramolecular chemistry is a useful methodology for construction of nano- or micro-sized objects and can significantly contribute to nanotechnology through so-called bottom-up processing. In addition, supramolecular self-assembled structures can mimic some aspects of biological systems. Bio-related functions such as molecular sensing, controlled release, signaling and materials separations have been realized. Supramolecular chemistry is a multidisciplinary field that includes subjects such as molecular design and nanosized materials. In this article recent examples of supramolecular chemistry in the context of biological therapy are introduced and classified into five categories: small supramolecular systems; designer polymers; self-assembled structures; predesigned assemblies; and nanomaterials. Finally, hierarchic organization of supramolecular structures for advanced functions is introduced to illustrate future directions of investigation. We hope that scientists studying therapeutic applications receive inspiration from this review to exploit the opportunities offered by supramolecular chemistry in their respective research areas.
机译：超分子化学是一种用于构建纳米或微米级物体的有用方法，并且可以通过所谓的自下而上的处理对纳米技术做出重大贡献。另外，超分子自组装结构可以模拟生物系统的某些方面。已经实现了与生物相关的功能，例如分子感测，控制释放，信号传导和材料分离。超分子化学是一个多学科领域，包括分子设计和纳米材料等学科。在本文中，介绍了生物治疗领域中超分子化学的最新实例，并将其分为五类：小型超分子系统;设计聚合物;自组装结构;预先设计的组件;和纳米材料。最后，介绍了用于高级功能的超分子结构的分层组织，以说明未来的研究方向。我们希望研究治疗应用的科学家能从这次综述中得到启发，以利用超分子化学在各自研究领域中提供的机会。

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