Monoclonal antibodies for the treatment of osteoarthritis

Zheng Shuang; Hunter David J.; Xu Jianhua; Ding Changhai

首页> 外文期刊>Expert opinion on biological therapy >Monoclonal antibodies for the treatment of osteoarthritis

【24h】

Monoclonal antibodies for the treatment of osteoarthritis

机译：单克隆抗体治疗骨关节炎

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Introduction: Osteoarthritis (OA) is a multifactorial chronic joint disease, and so far, there are no approved disease-modifying anti-OA drugs (DMOADs). There is an urgent need to develop therapies for different phenotypes of OA. Monoclonal antibodies (mAb) may slow structural progression, control inflammation and relieve pain, and thus have the potential to be DMOADs.

机译：简介：骨关节炎（OA）是一种多因素慢性关节疾病，到目前为止，尚无批准的可缓解疾病的抗OA药物（DMOAD）。迫切需要开发针对OA的不同表型的疗法。单克隆抗体（mAb）可能会减缓结构进程，控制炎症并缓解疼痛，因此有可能成为DMOAD。

著录项

来源
《Expert opinion on biological therapy》 |2016年第12期|共12页
作者
Zheng Shuang; Hunter David J.; Xu Jianhua; Ding Changhai;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
Inflammation; OA; DMOADs; mAbs;

机译：炎症;OA;DMOADs;mAbs;

相似文献

外文文献
中文文献
专利

1. Monoclonal antibodies for the treatment of osteoarthritis [J] . Zheng Shuang, Hunter David J., Xu Jianhua, Expert opinion on biological therapy . 2016,第12期

机译：单克隆抗体治疗骨关节炎
2. AMG 145, a monoclonal antibody against PCSK9, facilitates achievement of national cholesterol education program-adult treatment panel III low-density lipoprotein cholesterol goals among high-risk patients: An analysis from the LAPLACE-TIMI 57 trial (LDL-C assessment with PCSK9 monoclonaL antibody inhibition combined with statin thErapy-thrombolysis in myocardial infarction 57) [J] . DesaiN.R., GiuglianoR.P., ZhouJ., Journal of the American College of Cardiology . 2014,第5期

机译：AMG 145是针对PCSK9的单克隆抗体，可促进高危患者中国家胆固醇教育计划-成人治疗小组III低密度脂蛋白胆固醇目标的实现：来自LAPLACE-TIMI 57试验的分析（使用PCSK9 monoclonaL进行LDL-C评估抗体抑制联合他汀类药物治疗心肌梗塞溶栓57）
3. The Inhibitory Effect of CD46, CD55, and CD59 on Complement Activation After Immunotherapeutic Treatment of Cervical Carcinoma Cells with Monoclonal Antibodies or Bispecific Monoclonal Antibodies [J] . Kyra A Gelderman, Vanessa T Blok, Gert Jan Fleuren, Laboratory investigation . 2002,第4期

机译：单克隆抗体或双特异性单克隆抗体对宫颈癌细胞的免疫治疗后，CD46，CD55和CD59对补体激活的抑制作用
4. A Mathematical Model for Assessing KRAS Mutation Effect on Monoclonal Antibody Treatment of Colorectal Cancer [C] . Sheema Sameen, Roberto Barbuti, Paolo Milazzo, International Conference on Software Engineering and Formal Methods . 2015

机译：评估克拉斯突变对直肠癌单克隆抗体治疗的数学模型
5. Development of Monoclonal Antibodies for the Treatment of Bacterial Infections [D] . Wang Lin, Shun Xin. 2018

机译：治疗细菌感染的单克隆抗体的开发
6. The synovial membrane in osteoarthritis: a histological study including the characterisation of the cellular infiltrate present in inflammatory osteoarthritis using monoclonal antibodies. [O] . P A Revell, V Mayston, P Lalor, 1988

机译：骨关节炎中的滑膜：一种组织学研究包括使用单克隆抗体表征炎性骨关节炎中存在的细胞浸润。
7. The synovial membrane in osteoarthritis: a histological study including the characterisation of the cellular infiltrate present in inflammatory osteoarthritis using monoclonal antibodies. [O] . Revell, P A, Mayston, V, Lalor, P, 1988

机译：骨关节炎中的滑膜：一种组织学研究，包括使用单克隆抗体表征炎性骨关节炎中存在的细胞浸润。

Monoclonal antibodies for the treatment of osteoarthritis

摘要

著录项

相似文献

相关主题

期刊订阅