Pembrolizumab for the treatment of non-small cell lung cancer

Lim Sung Hee; Sun Jong-Mu; Lee Se-Hoon; Ahn Jin Seok; Park Keunchil; Ahn Myung-Ju

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Pembrolizumab for the treatment of non-small cell lung cancer

机译：派姆单抗治疗非小细胞肺癌

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Introduction: Immune checkpoint inhibitors targeting programmed death protein 1 (PD-1) receptor and its ligand, PD-L1, have recently led to significant and durable improvements in the clinical outcomes of some types of cancers including lung cancer.

机译：简介：靶向程序性死亡蛋白1（PD-1）受体及其配体PD-L1的免疫检查点抑制剂最近已导致包括肺癌在内的某些类型癌症的临床结局显着且持久的改善。

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来源
《Expert opinion on biological therapy》 |2016年第3期|共10页
作者
Lim Sung Hee; Sun Jong-Mu; Lee Se-Hoon; Ahn Jin Seok; Park Keunchil; Ahn Myung-Ju;
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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
non-small cell lung cancer; pembrolizumab;

机译：非小细胞肺癌;派姆单抗;

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专利

1. Rapid Response of Advanced Squamous Non-Small Cell Lung Cancer with Thrombocytopenia after First-Line Treatment with Pembrolizumab Plus Autologous Cytokine-Induced Killer Cells [J] . Zhenzhen Hui, Xinwei Zhang, Baozhu Ren, Frontiers in Immunology . 2015,第4期

机译：派姆单抗加自体细胞因子诱导的杀伤细胞一线治疗后，晚期鳞状非小细胞肺癌伴血小板减少的快速反应
2. The evolving use of pembrolizumab in combination treatment approaches for non-small cell lung cancer [J] . Alexander Mariam, Ko Brian, Lambert Remy, Expert review of respiratory medicine . 2020,第1a6期

机译：非小细胞肺癌组合治疗方法的不断发展使用
3. Treatment rationale and design of the PROLONG study: safety and efficacy of pembrolizumab as first-line therapy for elderly patients with non-small cell lung cancer [J] . International journal of applied mechanics . 2020,第3期

机译：治疗理由和设计延长研究：Pembrolizumab作为老年非小细胞肺癌患者的一线治疗的安全性和疗效
4. SAHA Treatment Reveals the Link between Histone Lysine Acetylation and Proteome in Non-small Cell Lung Cancer A549 Cells [C] . Quan Wu, Weiqing Xu, Lejie Cao, ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：Saha治疗揭示了非小细胞肺癌A549细胞中组蛋白赖氨酸乙酰化和蛋白质组之间的联系
5. A Study of Erlotinib Monotherapy and in Combination with Pembrolizumab in Previously Untreated Stage I-IIIA Non-small Cell Lung Cancer [D] . Liu, Qiong. 2021

机译：Erlotinib单疗法和蛋白质在先前未处理阶段I-IIIA非小细胞肺癌中的研究
6. Rapid Response of Advanced Squamous Non-Small Cell Lung Cancer with Thrombocytopenia after First-Line Treatment with Pembrolizumab Plus Autologous Cytokine-Induced Killer Cells [O] . Zhenzhen Hui, Xinwei Zhang, Baozhu Ren, 2015

机译：派姆单抗加自体细胞因子诱导的杀伤细胞一线治疗后晚期鳞状非小细胞肺癌伴血小板减少的快速反应
7. An open-label, randomized, phase I/II trial of IO102 and pembrolizumab, or IO102, pembrolizumab and chemotherapy, as first-line treatment for patients with metastatic non-small cell lung cancer [O] . J. Spicer, M. Provencio, P. Garrido Lopez, 2019

机译：IO102和Pembrolizumab或IO102，Pembrozumab和化疗的开放标签，随机，阶段I / II试验，作为转移性非小细胞肺癌患者的一线治疗

Pembrolizumab for the treatment of non-small cell lung cancer

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