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Regeneration of teeth using stem cell-based tissue engineering.

机译:使用基于干细胞的组织工程进行牙齿再生。

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摘要

Tooth autotransplantation, allotransplantation and dental implants have existed for many years, but have never been totally satisfactory. Thus, the development of new methods of tooth replacement has become desirable, and with the increasing knowledge of stem cell biology becomes a realistic possibility. Stem cell-based tissue engineering involving the recapitulation of the embryonic environment demonstrates that dental, non-dental, embryonic and adult stem cells can contribute to teeth formation in the appropriate setting. Evidence that stem cell populations may be present in human teeth provides the opportunity to consider biological tooth replacement 'new for old'.
机译:牙齿自体移植,同种异体移植和牙齿植入物已经存在了很多年,但从未完全令人满意。因此,开发新的牙齿替代方法变得令人期望,并且随着对干细胞生物学知识的增加,这成为了现实的可能性。基于干细胞的组织工程涉及胚胎环境的概括,表明在适当的环境中,牙齿,非牙齿,胚胎和成体干细胞可以促进牙齿的形成。人类牙齿中可能存在干细胞种群的证据为考虑生物牙齿置换“新旧结合”提供了机会。

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