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Psoriatic arthritis and TNF inhibitors: advances on effectiveness and toxicity

机译:银屑病关节炎和TNF抑制剂:有效性和毒性研究进展

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摘要

Over the last decade, due to the high expectations that biologic drugs like anti-TNF are raising, the appropriate identification of patients eligible for these treatments has been conditioned by numerous ordinary aspects, mainly represented by previous or ongoing comorbidities and related therapies, and chronic infections or recurrence of acute infections. Additionally, in the last years, due to close monitoring by experienced clinicians, remarkable changes have been also obtained in the field of safety. Another question mark refers to the management of psoriatic arthritis systemic manifestations, in which the impact of biologic therapy is not enough explored.
机译:在过去的十年中,由于人们对抗TNF等生物药物的期望值很高,因此对这些患者的资格进行适当鉴定的前提是许多普通方面,主要是以前或正在进行的合并症和相关疗法,以及慢性感染或急性感染复发。另外,在过去的几年中,由于经验丰富的临床医生的密切监视,在安全领域也发生了显着变化。另一个问号涉及牛皮癣性关节炎系统性表现的管理,其中对生物疗法的影响尚未充分探讨。

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