Biologics in Crohn's disease: searching indicators for outcome.

van-derWoude CJ; Hommes DW

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Biologics in Crohn's disease: searching indicators for outcome.

机译：克罗恩病中的生物制剂：寻找结果指标。

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New insights into the underlying mechanism of Crohn's disease is enabling the development of new therapies. Even though the mechanisms of these drugs have been studied extensively, reliable indicators for implementation of new biologic drugs are still needed. This review presents biologics in Crohn's disease focusing on efficacy, steroid sparing, mucosal healing and safety, including immunogenicity.

机译：对克罗恩病潜在机制的新见解正在推动新疗法的发展。尽管已经对这些药物的机理进行了广泛的研究，但仍需要可靠的指标来实施新的生物药物。这篇综述介绍了克罗恩病的生物制剂，重点是功效，类固醇保护，粘膜愈合和安全性，包括免疫原性。

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《Expert opinion on biological therapy》 |2007年第8期|共11页
作者
van-derWoude CJ; Hommes DW;
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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
Crohn's disease; Biological Products; Review Publication Type; development aspects; 生物制品;

机译：Crohn's disease;Biological Products;Review [Publication Type];development aspects;生物制品;

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专利

1. Biologics in Crohn's disease: searching indicators for outcome. [J] . van-derWoude CJ, Hommes DW Expert opinion on biological therapy . 2007,第8期

机译：克罗恩病中的生物制剂：寻找结果指标。
2. Biological considerations in locally advanced breast cancer treated with anthracycline-based neoadjuvant chemotherapy: thymidine labelling index is an independent indicator of clinical outcome. [J] . Ozmen V, Cabioglu N, Dolay K, Breast cancer research and treatment. . 2001,第2期

机译：基于蒽环类新辅助化疗治疗的局部晚期乳腺癌的生物学考虑：胸苷标记指数是临床结果的独立指标。
3. Strictureplasty in Selected Crohn's Disease Patients Results in Acceptable Long-term Outcome. [J] . Felipe Bellolio, Zane Cohen, Helen M Macrae, Diseases of the Colon and Rectum . 2012,第8期

机译：在某些克罗恩病患者中进行角膜成形术可获得可接受的长期结果。
4. Programmed Probiotics for Localized Delivery of a Model Biologic to Treat Crohn’s Disease [C] . McKayR., HaukP., BentleyW.E. Bioengineering and Translational Medicine Conference . 2018

机译：编程的益生菌，用于局部交付模型生物学治疗克罗恩病
5. Quantifying disease progression trajectory and investigating the impact of early initiation of biologic therapy in patients with Crohn's disease using the Lemann index of cumulative bowel damage. [D] . Panchal, Hina J. 2017

机译：使用累积肠损伤的Lemann指数量化疾病进展轨迹，并研究早期开始生物治疗对克罗恩病患者的影响。
6. Indicators of suboptimal biologic therapy over time in patients with ulcerative colitis and Crohns disease in the United States [O] . Haridarshan Patel, Trevor Lissoos, David T. Rubin -1

机译：美国溃疡性结肠炎和克罗恩氏病患者随着时间推移的次优生物治疗指标
7. P513 Assessment of quality indicators in The Swedish Inflammatory Bowel Disease Registry (SWIBREG) for Crohn’s Disease treated with biological therapies [O] . C Xu, V Byman, J Hossain, 2021

机译：P513评估瑞典炎症性肠病疾病注册表（束刺）的质量指标，用于用生物疗法治疗克罗恩病

Biologics in Crohn's disease: searching indicators for outcome.

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