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首页> 外文期刊>European addiction research >Chronological relationship between antisocial personality disorder and alcohol dependence.
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Chronological relationship between antisocial personality disorder and alcohol dependence.

机译：反社会人格障碍与酒精依赖之间的年代关系。

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Personality disorders, and particularly antisocial personality disorder (ASPD), frequently co-occur with alcohol dependence. ASPD is considered to be an important cofactor in the pathogenesis and clinical course of alcohol dependence. The chronological relationship between the onset of symptoms of ASPD and alcohol-dependence characteristics has not yet been studied in great detail and the role of ASPD in classification schemes of alcohol dependence as suggested by Cloninger and Schuckit has yet to be determined. We studied 55 alcohol-dependent patients to assess the prevalence and age at manifestation of ASPD, conduct disorder characteristics as well as alcohol dependence by employing the Semi-Structured Assessment for the Genetics of Alcoholism and the Structured Clinical Interview for DSM-III-R. Results indicate that the onset of ASPD characteristics precede that of alcohol dependence by some 4 years. This finding suggests that in patients with ASPD, alcohol dependence might be a secondary syndrome as suggested by previous research.
机译：人格障碍，尤其是反社会人格障碍（ASPD），经常与酒精依赖症同时发生。在酒精依赖的发病机理和临床过程中，ASPD被认为是重要的辅助因子。尚未详细研究ASPD症状发作与酒精依赖特征之间的时间关系，而Cloninger和Schuckit提出的ASPD在酒精依赖分类方案中的作用尚未确定。我们研究了55名酒精依赖患者，以通过对酒精中毒遗传学进行半结构评估和DSM-III-R的结构化临床访谈，评估ASPD表现的患病率和年龄，行为障碍特征以及酒精依赖。结果表明，ASPD特征的发作比酒精依赖的发作早了大约4年。这一发现表明，在ASPD患者中，酒精依赖可能是继发研究的继发性综合征。

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