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首页> 外文期刊>Genome >Estimating meiotic chromosome pairing and recombination parameters in telocentric trisomics
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Estimating meiotic chromosome pairing and recombination parameters in telocentric trisomics

机译：估计端粒三体组的减数分裂染色体配对和重组参数

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摘要

Telocentric trisomics (telotrisomics; one arm of a metacentric chromosome present in addition to two complete genomes) are used in theoretical studies of pairing affinities and chiasma formation in competitive situations and applied in genome analysis, gene localization, gene transfer, and breakage of close linkages. These applications require knowledge of the recombination characteristics of telotrisomics. Appropriate cytological and molecular markers and favorable chromosome morphology are not always available or applicable for quantitative analyses. We developed new mathematical models for extracting the maximum information from simple metaphase I observations. Two types of telotrisomics of the short arm of chromosome 1R of rye (Secale cereale), including several genotypes, were used as test material. In simple telotrisomics, pairing between morphologically identical complete chromosomes was more frequent than pairing between the telocentric and either of the normal chromosomes. In the telocentric substitution, morphologically identical telocentrics paired less frequently with each other than either one with the normal chromosome. Pairing partner switch was significant. Interaction between the two arms was variable. Variation within plants was considerable. Telotrisomics without markers are suitable for analyzing pairing preferences, for gene localization and gene transfer, and for breaking tight linkages, but less so for genome analysis.
机译：端粒三体组学（telotrisomics;除了两个完整的基因组外，还存在一个亚中心染色体的臂）用于竞争情况下配对亲和力和chiasma形成的理论研究，并应用于基因组分析，基因定位，基因转移和紧密连接的断裂。这些应用要求了解四线体组学的重组特征。适当的细胞学和分子标记以及有利的染色体形态并不总是可用或不适用于定量分析。我们开发了新的数学模型，以从简单的中期I观测中提取最大信息。黑麦（Secale谷类）1R染色体短臂的两种线粒体基因组，包括几种基因型，被用作测试材料。在简单的线粒体学中，形态相同的完整染色体之间的配对比端中心染色体和任何正常染色体之间的配对更为频繁。在端中心置换中，形态相同的端中心彼此的配对频率比与正常染色体中的任何一个频率更低。配对伙伴切换非常重要。两只手臂之间的相互作用是可变的。植物内的差异很大。没有标记的四体染色体组适合于分析配对偏好，基因定位和基因转移以及打破紧密的联系，但对于基因组分析则不太适合。

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