Strategies for Companies Targeting GPCRs: Emerging Tools and Methodologies for Screening and Discovery Are Improving Odds for Success

James Netterwald

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Strategies for Companies Targeting GPCRs: Emerging Tools and Methodologies for Screening and Discovery Are Improving Odds for Success

机译：针对GPCR的公司的策略：新兴的筛选和发现工具和方法正在提高成功几率

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In the organism, communication occurs at both the macro and the micro level. At the micro level—inside the cell—communication occurs between proteins relaying messages along signal-transduction pathways from both the internal and external to various compartments within the cell through the process of signal transduction. GPCRs are at the center of many signal-transduction pathways, and as a result, they are the subject of many basic biological research studies, as well as prime drug targets.

机译：在有机体中，交流发生在宏观和微观两个层面。在细胞内部的微观水平上，蛋白质之间发生通信，这些信号沿着信号转导途径通过信号转导过程从内部和外部到细胞内各个区室的信号转导途径传递信息。 GPCR是许多信号转导途径的中心，因此，它们是许多基础生物学研究以及主要药物靶标的主题。

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《Genetic Engineering & Biotechnology News: The Information Source of the Biotechnology Industry》 |2009年第20期|共2页
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James Netterwald;
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1. Strategies for Companies Targeting GPCRs: Emerging Tools and Methodologies for Screening and Discovery Are Improving Odds for Success [J] . James Netterwald Genetic Engineering & Biotechnology News: The Information Source of the Biotechnology Industry . 2009,第20期

机译：针对GPCR的公司的策略：新兴的筛选和发现工具和方法正在提高成功几率
2. Emerging Approaches to GPCR Ligand Screening for Drug Discovery [J] . Kumari Punita, Ghosh Eshan, Shukla Arun K. Trends in molecular medicine . 2015,第11期

机译：用于药物发现的GPCR配体筛选的新兴方法
3. GPCR Drug Discovery: Emerging Targets, Novel Approaches and Future Trends [J] . Zhou Jia, Wild Christopher Current topics in medicinal chemistry . 2019,第16期

机译：GPCR药物发现：新兴的目标，新方法和未来趋势
4. Towards a high-throughput drug discovery platform for the screening of GPCR targets in cells [C] . Prazeres D M F, Martins S A M, Trabuco J R C, 1st Portuguese Meeting in Bioengineering . 2011

机译：迈向筛选细胞中GPCR靶标的高通量药物发现平台
5. A study of the relationships between a target company's core competencies and the United States company's decision to acquire an overseas company in an emerging country. [D] . Saengwannagul, Pongrapee. 1997

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Strategies for Companies Targeting GPCRs: Emerging Tools and Methodologies for Screening and Discovery Are Improving Odds for Success

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