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首页> 外文期刊>Genomics >Analysis and characterization of an odorant receptor gene cluster in the zebrafish genome.
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Analysis and characterization of an odorant receptor gene cluster in the zebrafish genome.

机译:斑马鱼基因组中的气味受体基因簇的分析和表征。

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摘要

A 140.7-kb segment of zebrafish genomic DNA known to contain odorant receptor (OR) genes was fully sequenced to characterize more completely the organization of this gene cluster. A total of 20 OR genes were identified in this region. The most highly related genes are grouped in closest proximity to one another and in the same transcriptional orientation, indicating that a series of tandem duplications was responsible for the expansion of the OR gene family in teleost fish. Our analysis also revealed sequences that may be involved in the transcriptional regulation of OR genes within the cluster. Copyright 2001 Academic Press.
机译:斑马鱼基因组DNA的一个140.7-kb片段,已知包含气味受体(OR)基因,已被完全测序,以更完整地表征该基因簇的组织。在该区域总共鉴定出20个OR基因。高度相关的基因以彼此最接近的位置并以相同的转录方向分组,这表明一系列串联重复是硬骨鱼OR基因家族扩展的原因。我们的分析还揭示了可能与簇内OR基因的转录调控有关的序列。版权所有2001学术出版社。

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