A firm grip does not always pay off: a new Phact(r) 4 integrin signaling.

Sun Z; Fassler R

首页> 外文期刊>Genes and Development: a Journal Devoted to the Molecular Analysis of Gene Expression in Eukaryotes, Prokaryotes, and Viruses >A firm grip does not always pay off: a new Phact(r) 4 integrin signaling.

【24h】

A firm grip does not always pay off: a new Phact(r) 4 integrin signaling.

机译：牢牢把握并不一定总能带来回报：新的Phact（r）4整合素信号传导。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

beta1 integrin signaling plays crucial roles in enteric nervous system development. Zhang and colleagues (pp. 69-81) discovered that phosphatase and actin regulator 4 (Phactr4) antagonizes beta1 integrin signaling through protein phosphatase 1 (PP1) in focal adhesions of enteric neural crest cells (ENCCs). Loss of Phactr4-PP1 interaction leads to increased beta1 integrin signaling, loss of collective and directional migration, and hindgut hypogangaliosis, indicating that the right adjustment of beta1 integrin signaling is required for the normal migration and organization of ENCCs.

机译：beta1整合素信号传导在肠道神经系统发育中起关键作用。 Zhang及其同事（第69-81页）发现，磷酸酶和肌动蛋白调节剂4（Phactr4）在肠神经c细胞（ENCC）的粘着斑中通过蛋白磷酸酶1（PP1）拮抗β1整联蛋白信号传导。 Phactr4-PP1相互作用的丧失导致增加的beta1整合素信号传导，集体和定向迁移的损失以及后肠神经节低下，表明对ENCC的正常迁移和组织需要正确调节beta1整合素信号传导。

著录项

来源
《Genes and Development: a Journal Devoted to the Molecular Analysis of Gene Expression in Eukaryotes, Prokaryotes, and Viruses》 |2012年第1期|共5页
作者
Sun Z; Fassler R;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类医学遗传学;
关键词

相似文献

外文文献
中文文献
专利

1. A firm grip does not always pay off: a new Phact(r) 4 integrin signaling. [J] . Sun Z, Fassler R Genes and Development: a Journal Devoted to the Molecular Analysis of Gene Expression in Eukaryotes, Prokaryotes, and Viruses . 2012,第1期

机译：牢牢把握并不一定总能带来回报：新的Phact（r）4整合素信号传导。
2. TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling. [J] . Thodeti CK, Matthews B, Ravi A, Circulation research: a journal of the American Heart Association . 2009,第9期

机译：TRPV4通道通过整合素到整合素的信号传导介导循环应变诱导的内皮细胞重新定向。
3. Essential role of integrin-linked kinase in podocyte biology: Bridging the integrin and slit diaphragm signaling. [J] . Dai C, Stolz DB, Bastacky SI, Journal of the American Society of Nephrology: JASN . 2006,第8期

机译：整合素相关激酶在足细胞生物学中的重要作用：整合整合素和缝隙隔膜信号。
4. MARKET VALUES, EARNINGS AND DIVIDENDS: DIFFERENCES BETWEEN FIRMS PAYING DIVIDENDS AND FIRMS NOT PAYING DIVIDENDS [C] . Gun-Ho Joh, James E. Williamson Proceedings of the thirty-second annual meeting of the Western Decision Sciences Institute . 2003

机译：市场价值，收益和股息：公司支付股息与未支付股息的公司之间的差异
5. SNARE-mediated control of integrin trafficking, cell-ECM adhesion and focal adhesion signaling. [D] . Skalski, Michael. 2011

机译：SNARE介导的整联蛋白运输，细胞ECM粘附和局灶性粘附信号转导的控制。
6. A firm grip does not always pay off: a new Phact(r) 4 integrin signaling [O] . Zhiqi Sun, Reinhard Fässler 1910

机译：牢牢把握并非总能取得回报：新的Phact（r）4整合素信号
7. A firm grip does not always pay off: a new Phact(r) 4 integrin signaling [O] . Sun, Zhiqi, Fässler, Reinhard 2012

机译：牢牢把握并非总能取得回报：新的Phact（r）4整合素信号

A firm grip does not always pay off: a new Phact(r) 4 integrin signaling.

摘要

著录项

相似文献

相关主题

期刊订阅