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Novel bioactive coatings for biomedical applications deposited by electrophoretic deposition

机译:通过电泳沉积沉积的新型生物活性涂料,用于生物医学应用

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摘要

There are thousands of implant operations every year that give significant pain relief to patients. Even small improvements can reduce the need for further revision surgery. Improving the bonding of an implant, by using a bioactive coating, increases the rate of fixture of the implant, reducing the healing time. The original artificial bioactive coatings, calcium phosphates and hydroxyapatite, were absorbed quickly by the body. This leaves the substrate bare, resulting in loosening of the implant. Hench developed bioactive glass ceramics in the 1970s that were longer lasting and bonded to bone. Due to the low fracture toughness of these glass ceramics, these materials are used for non-load bearing components, or more commonly, as coatings. This paper shows that fluorapatite-mullite coatings can be successfully deposited as a glass ceramic. Initial bio activity tests using SBF show that this coating is biologically active.
机译:每年有成千上万的植入手术使患者的疼痛明显减轻。即使是很小的改进也可以减少进一步修整手术的需要。通过使用生物活性涂层来改善植入物的结合力,可以提高植入物的固定率,缩短愈合时间。原始的人工生物活性涂层磷酸钙和羟基磷灰石被人体迅速吸收。这使衬底裸露,导致植入物松动。亨克斯在1970年代开发了生物活性玻璃陶瓷,这种陶瓷具有更长的使用寿命并与骨骼结合。由于这些玻璃陶瓷的断裂韧性低,因此这些材料用于非承重部件,或更常见地用作涂层。本文表明,氟磷灰石-莫来石涂层可以成功地作为玻璃陶瓷沉积。使用SBF进行的初步生物活性测试表明该涂层具有生物活性。

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