PROCEEDINGS OF THE DUTCH SOCIETY OF CLINICAL PHARMACOLOGY AND BIOPHARMACY MEETING OF SEPTEMBER 27TH 2006 Dipyridamole enhances ischemia-induced reactive hyperemia by increased adenosine receptor stimulation.

P. Meijer; N. Riksen; G. J. Scheffer; P. Smits; G. A. Rongen

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PROCEEDINGS OF THE DUTCH SOCIETY OF CLINICAL PHARMACOLOGY AND BIOPHARMACY MEETING OF SEPTEMBER 27TH 2006 Dipyridamole enhances ischemia-induced reactive hyperemia by increased adenosine receptor stimulation.

机译：临床药理学和生物医学会议荷兰学会的程序2006年9月27日，双嘧达莫通过增加腺苷受体刺激来增强缺血性反应性充血。

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Introduction: Dipyridamole enhances post-occlusive reactive hyper-emia (PORH) in the human forearm. The mechanism of this poten-tiation remains to be elucidated. We hypothesize that dipyridamole augments PORH by increasing interstitial adenosine and subsequent stimulation of adenosine receptors. To test this hypothesis, the effect of caffeine (an adenosine A1 and A2 receptor antagonist) on dipyri-damole-induced augmentation of PORH was explored.

机译：简介：双嘧达莫可增强人前臂的闭塞后反应性充血（PORH）。这种增强作用的机制尚待阐明。我们假设双嘧达莫通过增加间质腺苷和随后的腺苷受体刺激来增加PORH。为了验证这一假设，研究了咖啡因（腺苷A1和A2受体拮抗剂）对双嘧达莫-诱导的PORH增强的作用。

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来源
《British Journal of Clinical Pharmacology》 |2007年第4期|共2页
作者
P. Meijer; N. Riksen; G. J. Scheffer; P. Smits; G. A. Rongen;
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正文语种 eng
中图分类药学;
关键词
Dipyridamole; Receptors; Purinergic P1; reactive hyperemia; Ischemia; Dutch Population; 双嘧达莫; 受体; 嘌呤能P1; 局部缺血;

机译：Dipyridamole;Receptors;Purinergic P1;reactive hyperemia;Ischemia;Dutch Population;双嘧达莫;受体;嘌呤能P1;局部缺血;

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1. PROCEEDINGS OF THE DUTCH SOCIETY OF CLINICAL PHARMACOLOGY AND BIOPHARMACY MEETING OF SEPTEMBER 27TH 2006 Dipyridamole enhances ischemia-induced reactive hyperemia by increased adenosine receptor stimulation. [J] . P. Meijer, N. Riksen, G. J. Scheffer, British Journal of Clinical Pharmacology . 2007,第4期

机译：临床药理学和生物医学会议荷兰学会的程序2006年9月27日，双嘧达莫通过增加腺苷受体刺激来增强缺血性反应性充血。
2. PROCEEDINGS OF THE DUTCH SOCIETY OF CLINICAL PHARMACOLOGY AND BIOPHARMACY MEETING OF SEPTEMBER 27TH 2006 Development strategy and potential impact on medication safety for clinical rules: the lithium case [J] . S. J. W. Wessels-Basten British Journal of Clinical Pharmacology . 2007,第4期

机译：2006年9月27日荷兰临床药理学和生物制药会议的程序发展策略及其对临床规则对药物安全性的潜在影响：锂病例
3. PROCEEDINGS OF THE DUTCH SOCIETY OF CLINICAL PHARMACOLOGY AND BIOPHARMACY MEETING OF SEPTEMBER 27TH 2006 Non-detectable levels of 6-thioguanine nucleotides and 6-methylmercaptopurine in a patient treated with azathioprine: a case report [J] . D. R. Wong, M. O. den Dulk, L. J. J. Derijks, British Journal of Clinical Pharmacology . 2007,第4期

机译：临床药理学和生物医药学会议荷兰学会的程序2006年9月27日在硫唑嘌呤治疗的患者中未检测到6-硫鸟嘌呤核苷酸和6-甲基巯基嘌呤的水平：病例报告
4. Dipyridamole enhances ischemia-induced reactive hyperemia by increased adenosine receptor stimulation [O] . P Meijer, N Riksen, G-J Scheffer, 2007

机译：双嘧达莫通过增加腺苷受体刺激来增强缺血性反应性充血
5. Proceedings of the Dutch society for clinical pharmacology and biopharmacy, 11 April 2003: These abstracts have been accepted by the Dutch Society for Clinical Pharmacology and Biopharmacy [O] . 2004

机译：荷兰临床药理学和生物药学学会会刊，2003年4月11日：这些摘要已被荷兰临床药理学和生物药学学会接受

PROCEEDINGS OF THE DUTCH SOCIETY OF CLINICAL PHARMACOLOGY AND BIOPHARMACY MEETING OF SEPTEMBER 27TH 2006 Dipyridamole enhances ischemia-induced reactive hyperemia by increased adenosine receptor stimulation.

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