WiggleTools: parallel processing of large collections of genome-wide datasets for visualization and statistical analysis.

Zerbino DR; Johnson N; Juettemann T; Wilder SP; Flicek P

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WiggleTools: parallel processing of large collections of genome-wide datasets for visualization and statistical analysis.

机译：WiggleTools：并行处理大范围的全基因组数据集，以进行可视化和统计分析。

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MOTIVATION: Using high-throughput sequencing, researchers are now generating hundreds of whole-genome assays to measure various features such as transcription factor binding, histone marks, DNA methylation or RNA transcription. Displaying so much data generally leads to a confusing accumulation of plots. We describe here a multithreaded library that computes statistics on large numbers of datasets (Wiggle, BigWig, Bed, BigBed and BAM), generating statistical summaries within minutes with limited memory requirements, whether on the whole genome or on selected regions. AVAILABILITY AND IMPLEMENTATION: The code is freely available under Apache 2.0 license at www.github.com/Ensembl/Wiggletools

机译：动机：使用高通量测序，研究人员现在正在生成数百种全基因组测定，以测量各种特征，例如转录因子结合，组蛋白标记，DNA甲基化或RNA转录。显示如此多的数据通常会导致混乱的图积累。我们在这里描述了一个多线程库，该库可以计算大量数据集（摆动，BigWig，Bed，BigBed和BAM）的统计信息，并在几分钟内生成有限的内存或整个基因组或选定区域的统计摘要。可用性和实现：该代码可在Apache 2.0许可下免费获得，网址为www.github.com/Ensembl/Wiggletools

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《Bioinformatics》 |2014年第7期|共2页
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Zerbino DR; Johnson N; Juettemann T; Wilder SP; Flicek P;
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中图分类生物工程学（生物技术）;
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1. WiggleTools: parallel processing of large collections of genome-wide datasets for visualization and statistical analysis. [J] . Zerbino DR, Johnson N, Juettemann T, Bioinformatics . 2014,第7期

机译：WiggleTools：并行处理大范围的全基因组数据集，以进行可视化和统计分析。
2. Cscan: finding common regulators of a set of genes by using a collection of genome-wide ChIP-seq datasets [J] . Federico Zambelli, Gian Marco Prazzoli, Giulio Pavesi, Nucleic acids research . 2012,第W1期

机译：Cscan：通过使用全基因组的ChIP-seq数据集，找到一组基因的共同调控因子
3. Cscan: finding common regulators of a set of genes by using a collection of genome-wide ChIP-seq datasets [J] . Federico Zambelli, Gian Marco Prazzoli, Giulio Pavesi, Nucleic acids research . 2012,第W1期

机译：Cscan：通过使用全基因组的ChIP-seq数据集，找到一组基因的共同调控因子
4. Indexing and Parallel Query Processing Support for Visualizing Climate Datasets [C] . Su Yu, Agrawal Gagan, Woodring Jonathan 41st International Conference on Parallel Processing. . 2012

机译：索引和并行查询处理支持，以可视化气候数据集
5. Efficient visualization of large datasets using parallel processing and visibility computation. [D] . Shih, Po-Wen. 1999

机译：使用并行处理和可见性计算，对大型数据集进行高效可视化。
6. WiggleTools: parallel processing of large collections of genome-wide datasets for visualization and statistical analysis [O] . Daniel R. Zerbino, Nathan Johnson, Thomas Juettemann, -1

机译：WiggleTools：并行处理大范围的全基因组数据集以进行可视化和统计分析
7. WiggleTools: parallel processing of large collections of genome-wide datasets for visualization and statistical analysis [O] . D. R. Zerbino, N. Johnson, T. Juettemann, 2013

机译：WIGGLETOOLS：用于可视化和统计分析的大型基因组数据集的平行处理
8. Facility for Local Postprocessing, Visualization, and Animation of Remotely Simulated Very Large Temporal Datasets [R] . Hesthaven, J. S. 2001

机译：用于远程模拟的超大时间数据集的本地后处理，可视化和动画的工具

WiggleTools: parallel processing of large collections of genome-wide datasets for visualization and statistical analysis.

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