INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments

de Pretis Stefano; Kress Theresia; Morelli Marco J.; Melloni Giorgio E. M.; Riva Laura; Amati Bruno; Pelizzola Mattia

首页> 外文期刊>Bioinformatics >INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments

【24h】

INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments

机译：INSPEcT：一种计算工具，可从RNA和4sU-seq时程实验推断出mRNA的合成，加工和降解动力学

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Motivation: Cellular mRNA levels originate from the combined action of multiple regulatory processes, which can be recapitulated by the rates of pre-mRNA synthesis, pre-mRNA processing and mRNA degradation. Recent experimental and computational advances set the basis to study these intertwined levels of regulation. Nevertheless, software for the comprehensive quantification of RNA dynamics is still lacking.

机译：动机：细胞mRNA的水平源自多种调节过程的共同作用，这可以通过前mRNA合成，前mRNA加工和mRNA降解的速率进行概括。最近的实验和计算进展为研究这些相互关联的调节水平奠定了基础。然而，仍然缺乏用于RNA动力学的全面定量的软件。

著录项

来源
《Bioinformatics》 |2015年第17期|共7页
作者
de Pretis Stefano; Kress Theresia; Morelli Marco J.; Melloni Giorgio E. M.; Riva Laura; Amati Bruno; Pelizzola Mattia;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类生物工程学（生物技术）;
关键词

相似文献

外文文献
中文文献
专利

1. INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments [J] . de Pretis Stefano, Kress Theresia, Morelli Marco J., Bioinformatics . 2015,第17期

机译：INSPEcT：一种计算工具，可从RNA和4sU-seq时程实验推断出mRNA的合成，加工和降解动力学
2. New R&D tools against lead times and costs (part 1): Fields of application for computational fluid dynamics in control valve development [J] . Jorg Kiesbauer, Domagoj Vnucec Valve World . 2010,第3期

机译：针对交货时间和成本的新研发工具（第1部分）：控制阀开发中计算流体动力学的应用领域
3. New R&D tools against lead times and costs. part 2: Fields of application for computational fluid dynamics in control valve development [J] . Jorg Kiesbauer, Domagoj Vnucec Valve World . 2010,第4期

机译：针对交货时间和成本的新研发工具。第2部分：控制阀开发中计算流体动力学的应用领域
4. The role of perceptual failure and degrading processes in urban traffic accidents: a stochastic computational model for virtual experiments [C] . Florian Denk, Werner Huber, Pascal Brunner, IEEE International Conference on Intelligent Transportation Systems . 2020

机译：城市交通事故中感知失败和有辱人格过程的作用：虚拟实验的随机计算模型
5. A data processing strategy for the computational identification of novel mRNA transcripts and novel mRNA splice-forms from RNA-seq data generated by massively parallel sequencing. [D] . Darko, Samuel W. 2010

机译：一种从大规模并行测序产生的RNA-seq数据中计算鉴定新型mRNA转录物和新型mRNA剪接形式的数据处理策略。
6. INSPEcT-GUI Reveals the Impact of the Kinetic Rates of RNA Synthesis Processing and Degradation on Premature and Mature RNA Species [O] . Stefano de Pretis, Mattia Furlan, Mattia Pelizzola 2020

机译：Inspect-Gui揭示了RNA合成加工和降解的动力率对早产和成熟的RNA物种的影响
7. INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments [O] . Stefano de Pretis, Theresia Kress, Marco J. Morelli, 2015

机译：检查：从RNA和4SU-SEQ时间课程实验推断mRNA合成，处理和降解动态的计算工具

INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments

摘要

著录项

相似文献

相关主题

期刊订阅