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首页> 外文期刊>Berliner und Munchener Tierarztliche Wochenschrift >A follow up study on antibodies against Lawsonia intracellularis in mares and foals from two breeding farms in Germany
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A follow up study on antibodies against Lawsonia intracellularis in mares and foals from two breeding farms in Germany

机译：来自德国两个繁殖场的母马和小马中抗胞内劳森菌抗体的后续研究

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Equine proliferative enteropathy (EPE) caused by Lawsonia (L) intracellularis is an emerging disease in foals, particularly in North America. Since a case report in Germany exists, the objective of this study was to examine the incidence of L. infracellular/5-antibodies in healthy horses from two German breeding farms. In group 1, serum samples from 24 (year 1) and 16 (year 2) Haflinger mares and their foals were taken. In group 2, over a period of five months, serum samples of six warmblood mares and foals were collected monthly from birth until the foals became seronegative. Serum samples were tested using an ELISA system. Results are expressed as Percentage of Inhibiton (PI). All adult mares (100%) of both groups were seropositive at each point in time (Pl-value > 30). In group 1, 7/24 foals (29.2%) in year 1 and 4/16 foals (25%) in year 2 had antibodies. The seropositive foals from year 2 had the same dams as the seropositive foals from year 1. In group 2 five of six foals were seropositive after birth. Antibodies decreased from March to July in mares and foals. In July, all five foals tested negative for the first time between the ages of 82 and 141 days (median 115 days). Pi-values of mares were significantly correlated with Pl-values of their foals. Higher Pl-values were seen in younger foals and early in spring. Loss of antibodies in foals at the age of three to five months could be a risk factor for infection and appearance of EPE.
机译：由胞内劳索尼亚（L）引起的马增生性肠病（EPE）是小马驹中正在出现的疾病，尤其是在北美。由于存在德国的病例报告，因此本研究的目的是检查来自两个德国育种场的健康马中的L. infracellular / 5-抗体的发生率。在第1组中，从Haflinger母马及其驹中采集了24（第1年）和16（第2年）的血清样品。在第2组中，在五个月的时间内，从出生开始每月收集六只温血母马和小马的血清样品，直到小马血清呈阴性。使用ELISA系统测试血清样品。结果表示为抑制百分数（PI）。两组的所有成年母马（100％）在每个时间点均为血清阳性（Pl值> 30）。在第1组中，第1年的7/24小马驹（29.2％）和第2年的4/16小马驹（25％）有抗体。第2年的血清阳性小马驹与第1年的血清阳性小马鼠具有相同的坝。在第2组中，六只小马驹中有5只在出生后是血清阳性的。从三月到七月，母马和小马的抗体减少。在7月份，五只小马驹在82到141天（中位数115天）之间首次测试为阴性。母马的Pi值与它们的驹的Pl值显着相关。在年轻的小马驹和春季初发现较高的Pl值。三到五个月大的小马驹中抗体的丢失可能是感染和EPE出现的危险因素。

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