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首页> 外文期刊>Berliner und Munchener Tierarztliche Wochenschrift >A need to define characteristics to be used in the taxonomy of the expanding pestivirus genus.
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A need to define characteristics to be used in the taxonomy of the expanding pestivirus genus.

机译：需要定义在扩大的瘟病毒属的分类学中使用的特征。

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摘要

The relatively high rate of genetic drift observed with pestiviruses results not only in the emergence of new species but also in heterogeneity within recognized species. The grouping of pestiviruses into species was first based on host and to a lesser extent on clinical presentation, then later by antigenic comparisons and more recently genetic comparisons. Subgrouping within species is a more recent taxonomic development and has been based primarily on genetic comparisons. While there are a number of publications proposing new species within the Pestivirus genus or new subgroups within recognized pestivirus species, there is no consensus on the criteria required to declare a new species and subgroup. Defining the criteria used for segregation of species and subgroups within a species is important because differentiating viral species and subspecies and determining the regions in which they are endemic has profound implications for eradication efforts, the design of vaccines and for regulation of trade in livestock and animal derived products, such as fetal bovine serum. This review outlines criteria used for differentiating species within the different genera of the Flaviviridae, compares criteria previously used for differentiating pestiviruses and discusses the need for the development of a unified system for defining species and subgroups within the Pestivirus genus.
机译：在瘟病毒中观察到的相对较高的遗传漂移率不仅导致新物种的出现，而且导致公认物种内的异质性。瘟病毒按物种分类首先是基于宿主，其次是基于临床表现，然后是通过抗原比较和最近的遗传比较。物种内的亚分组是最近的分类学发展，并且主要基于遗传比较。尽管有许多出版物提出了瘟病毒属中的新物种或公认的瘟病毒物种中的新亚组的提议，但对于宣布新物种和亚组的标准尚无共识。定义用于物种内物种和亚群隔离的标准很重要，因为区分病毒物种和亚种并确定其特有区域对于根除努力，疫苗设计以及对畜牧业贸易的监管具有深远的意义。衍生产品，例如胎牛血清。这篇综述概述了用于区分黄病毒科不同属内的物种的标准，比较了以前用于区分瘟病毒的标准，并讨论了开发用于定义瘟疫病毒属内物种和亚组的统一系统的必要性。

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