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Western lifestyle: A 'master' manipulator of the intestinal microbiota?

机译:西方生活方式:肠道菌群的“大师”操纵者?

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摘要

There is growing awareness that lifestyle and life choices have a profound impact on the pathophysiology of many diseases. This is especially true in Western countries where diet-related chronic diseases are the single largest cause of morbidity and mortality, afflicting >50% of the adult population. These changes have happened relatively recently, beginning with the introduction of agriculture and animal husbandry around 10 000 years ago, meaning we are currently existing within a state of evolutionary discordance; our genome has, as yet, failed to adapt in response to the rapid change in its environment.
机译:人们日益意识到,生活方式和生活选择对许多疾病的病理生理学具有深远的影响。在与饮食有关的慢性疾病是发病率和死亡率的最大原因,折磨成年人口的50%以上的西方国家中,尤其如此。这些变化发生在相对较新的时期,始于大约一万年前的农业和畜牧业的引进,这意味着我们目前处于进化不和谐状态。迄今为止,我们的基因组未能适应环境的快速变化。

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