Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts

Ek Weronica E.; Reznichenko Anna; Ripke Stephan; Niesler Beate; Zucchelli Marco; Rivera Natalia V.; Schmidt Peter T.; Pedersen Nancy L.; Magnusson Patrik; Talley Nicholas J.; Holliday Elizabeth G.; Houghton Lesley; Gazouli Maria; Karamanolis George; Rappold Gudrun; Burwinkel Barbara; Surowy Harald; Rafter Joseph; Assadi Ghazaleh; Li Ling; Papadaki Evangelia; Gambaccini Dario; Marchi Santino; Colucci Rocchina; Blandizzi Corrado; Barbaro Raffaella; Karling Pontus; Walter Susanna; Ohlsson Bodil; Tornblom Hans; Bresso Francesca; Andreasson Anna; Dlugosz Aldona; Simren Magnus; Agreus Lars; Lindberg Greger; Boeckxstaens Guy; Bellini Massimo; Stanghellini Vincenzo; Barbara Giovanni; Daly Mark J.; Camilleri Michael; Wouters Mira M.; DAmato Mauro

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Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts

机译：探索肠易激综合症的遗传学：一项针对普通人群的GWA研究以及多国病例对照人群的复制

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Objective IBS shows genetic predisposition, but adequately powered gene-hunting efforts have been scarce so far. We sought to identify true IBS genetic risk factors by means of genome-wide association (GWA) and independent replication studies.

机译：客观的IBS显示出遗传易感性，但是到目前为止，缺乏足够动力的基因狩猎工作。我们试图通过全基因组关联（GWA）和独立复制研究来鉴定真正的IBS遗传危险因素。

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《Gut: Journal of the British Society of Gastroenterology》 |2015年第11期|共9页
作者
Ek Weronica E.; Reznichenko Anna; Ripke Stephan; Niesler Beate; Zucchelli Marco; Rivera Natalia V.; Schmidt Peter T.; Pedersen Nancy L.; Magnusson Patrik; Talley Nicholas J.; Holliday Elizabeth G.; Houghton Lesley; Gazouli Maria; Karamanolis George; Rappold Gudrun; Burwinkel Barbara; Surowy Harald; Rafter Joseph; Assadi Ghazaleh; Li Ling; Papadaki Evangelia; Gambaccini Dario; Marchi Santino; Colucci Rocchina; Blandizzi Corrado; Barbaro Raffaella; Karling Pontus; Walter Susanna; Ohlsson Bodil; Tornblom Hans; Bresso Francesca; Andreasson Anna; Dlugosz Aldona; Simren Magnus; Agreus Lars; Lindberg Greger; Boeckxstaens Guy; Bellini Massimo; Stanghellini Vincenzo; Barbara Giovanni; Daly Mark J.; Camilleri Michael; Wouters Mira M.; DAmato Mauro;
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正文语种 eng
中图分类消化系及腹部疾病;
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1. Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts [J] . Ek Weronica E., Reznichenko Anna, Ripke Stephan, Gut: Journal of the British Society of Gastroenterology . 2015,第11期

机译：探索肠易激综合症的遗传学：一项针对普通人群的GWA研究以及多国病例对照人群的复制
2. A GWAS GWAS meta‐analysis from 5 population‐based cohorts implicates ion channel genes in the pathogenesis of irritable bowel syndrome [J] . Bonfiglio F., Henstr?m M., Nag A., Neurogastroenterology and motility . 2018,第9期

机译：来自5个基于5名群体的群体的GWAS GWAS荟萃分析意味着肠易激综合征发病机制中的离子通道基因
3. The Prevalence of Intestinal Parasites Is Not Greater Among Individuals With Irritable Bowel Syndrome: A Population-based Case-control Study [J] . Krogsgaard Laura Rindom, Engsbro Anne Line, Stensvold Christen Rune, Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association . 2015,第3期

机译：肠易激综合征个体中肠道寄生虫的患病率不高：基于人群的病例对照研究
4. State-of-the Art Lecture: Irritable bowel syndrome: the new inflammatory bowel disease? [C] . R. C. SPILLE Falk Symposium . 2006

机译：最先进的讲座：肠易激综合征：新的炎症性肠病？
5. Irritable Bowel Syndrome and Vitamin D Insufficiency: The Effects of Vitamin D Level on Irritable Bowel Syndrome [D] . Pollock, Mary E. 2018

机译：肠易激综合征和维生素D功能：维生素D水平对肠易激综合征的影响
6. Impact of tonsillectomy on irritable bowel syndrome: A nationwide population-based cohort study [O] . Meng-Che Wu, Kevin Sheng-Kai Ma, Yu-Hsun Wang, 2020

机译：扁桃体切除术对肠易激综合征的影响：全国范围的群组队列研究
7. Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts [O] . Weronica E Ek, Anna Reznichenko, Stephan Ripke, 2014

机译：探索肠易肠综合征的遗传学：跨国案例控制队列的一般人群和复制的GWA研究

Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts

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