Brodalumab and ixekizumab, anti-interleukin-17-receptor antibodies for psoriasis: A critical appraisal

SpulsPh.I.; HooftL.

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Brodalumab and ixekizumab, anti-interleukin-17-receptor antibodies for psoriasis: A critical appraisal

机译：Brodalumab和ixekizumab，银屑病抗白介素17受体抗体：关键评估

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Aim Papp et al. (N Engl J Med 2012; 366: 1181-9) and Leonardi et al. (N Engl J Med 2012; 366: 1190-9) respectively assessed the efficacy and safety of brodalumab (AMG 827), a human monoclonal antibody directed against inter-leukin (rL)-17RA, die receptor of IL-17A and ixekizumab (LY2439821), a humanized anti-IL-17 monoclonal antibody for the treatment of moderate-to-severe plaque psoriasis.

机译：Aim Papp等。（N Engl J Med 2012; 366：1181-9）和Leonardi等人。（N Engl J Med 2012; 366：1190-9）分别评估了Brodalumab（AMG 827）的有效性和安全性，brodalumab是针对白介素（rL）-17RA的人单克隆抗体，是IL-17A和ixekizumab的受体（ LY2439821），一种用于治疗中度至重度斑块状牛皮癣的人源化抗IL-17单克隆抗体。

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《British Journal of Dermatology》 |2012年第4期|共4页
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SpulsPh.I.; HooftL.;
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正文语种 eng
中图分类皮肤病学与性病学;
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1. Response to brodalumab and ixekizumab, anti-interleukin-17-receptor antibodies for psoriasis: A critical appraisal [J] . LeonardiC. British Journal of Dermatology . 2012,第4期

机译：对牛皮癣抗白细胞介素17受体抗体brodalumab和ixekizumab的反应：关键评估
2. Brodalumab, a human anti-interleukin-17-receptor antibody in the treatment of Japanese patients with moderate-to-severe plaque psoriasis: Efficacy and safety results from a phase II randomized controlled study [J] . Nakagawa Hidemi, Niiro Hiroaki, Ootaki Kenji Journal of dermatological science . 2016,第1期

机译：Brodalumab，一种人类抗白介素17受体抗体，用于治疗日本中度至重度斑块状牛皮癣患者：II期随机对照研究的疗效和安全性结果
3. Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis [J] . PappK.A., LeonardiC., MenterA., The New England journal of medicine . 2012,第13期

机译：Brodalumab，牛皮癣的抗白细胞介素-17-受体抗体
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6. Psoriasis patients utilizing secukinumab ixekizumab or brodalumab – comparisons to prior biologic medication adherence levels reasons for switching and reported changes in disease symptoms [O] . Renee Baiano, Francis Staskon, Rick Miller 2019

机译：使用secukinumabixekizumab或brodalumab的牛皮癣患者-与先前生物药物依从性水平的比较转换原因以及报告的疾病症状变化
7. Short-Term Efficacy and Safety of IL-17, IL-12/23, and IL-23 Inhibitors Brodalumab, Secukinumab, Ixekizumab, Ustekinumab, Guselkumab, Tildrakizumab, and Risankizumab for the Treatment of Moderate to Severe Plaque Psoriasis: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials [O] . Fan Bai, Gang Gang Li, Qingmin Liu, 2019

机译：IL-17，IL-12/23和IL-23抑制剂Brodalumab，Secukinumab，Ixekizumab，Ustekizumab，Guselkumab，Tildrakizumab和Risankizumab的短期疗效和安全性用于治疗中度至重度斑块牛皮癣：系统审查和随机对照试验的网络荟萃分析

Brodalumab and ixekizumab, anti-interleukin-17-receptor antibodies for psoriasis: A critical appraisal

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