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首页> 外文期刊>Growth Factors >The level of vascular endothelial cell growth factor, nitric oxide, and endothelin-1 was correlated with ovarian volume or antral follicle counts: a potential predictor of pregnancy outcome in IVF.
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The level of vascular endothelial cell growth factor, nitric oxide, and endothelin-1 was correlated with ovarian volume or antral follicle counts: a potential predictor of pregnancy outcome in IVF.

机译:血管内皮细胞生长因子,一氧化氮和内皮素-1的水平与卵巢体积或窦房卵计数相关:IVF妊娠结局的潜在预测指标。

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The objective of this study was to investigate the correlation between the concentrations of vascular endothelial cell growth factor (VEGF), nitric oxide (NO), or endothelin-1 (ET-1) in follicular fluid with antral follicle counts (AFCs) or ovarian volume in order to predict the outcome of in vitro fertilization (IVF). One hundred and thirty-one patients were enrolled in this study, and the pregnancy rate was 37.4%. The concentration of VEGF or NO was significantly increased, while the concentration of ET-1 in follicular fluid was decreased in the group who became pregnant (P  0.05). The ovarian volume or AFC was significantly higher in groups that became pregnant (P  0.05). In addition, the ovarian volume or AFC was positively correlated with the concentration of VEGF or NO and negatively correlated with the concentration of ET-1 in follicular fluid. Our data suggest that these correlations may be associated with the successful pregnancies through IVF.
机译:这项研究的目的是调查与窦卵泡计数(AFC)或卵巢的卵泡液中血管内皮细胞生长因子(VEGF),一氧化氮(NO)或内皮素1(ET-1)的浓度之间的相关性量以预测体外受精(IVF)的结果。本研究共纳入131例患者,妊娠率为37.4%。怀孕组的卵泡液中VEGF或NO的浓度显着增加,而ET-1的浓度则降低(P <0.05)。怀孕组的卵巢体积或AFC显着更高(P <0.05)。此外,卵泡液中卵巢体积或AFC与VEGF或NO的浓度呈正相关,与ET-1的浓度呈负相关。我们的数据表明,这些相关性可能与通过IVF成功妊娠有关。

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