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Entropy

机译：熵

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摘要

The concept of entropy, originally derived from thermodynamics, has been successfully applied to EEG analysis. Various entropy algorithms have been used in clinical studies, but until now a commercially available monitor exists only for spectral entropy. By calculating two distinct values for the EEG dominated part of the spectrum (state entropy, SE) and the total spectrum (response entropy, RE), the M-Entropy module claims to provide useful information regarding the cortical state of the patient as well as an indirect measure of adequacy of analgesia. Generally, entropy has been studied for quantification of anaesthetic drug effect for various GABA-ergic i.v. induction agents and volatile anaesthetics like propofol and sevoflurane and overall was found comparable to the current clinical gold standard bispectral index (BIS). Entropy guidance may not be used during ketamine or nitrous oxide administration, since there is no reliable correlation to the patient's state of consciousness. The usefulness of RE as a surrogate for increased EMG activity due to painful stimulation has not been proven so far.
机译：最初源自热力学的熵的概念已成功地应用于脑电分析。在临床研究中已经使用了各种熵算法，但是直到现在，仅存在用于频谱熵的商用监视器。通过计算EEG占主导地位的频谱部分（状态熵SE）和总频谱（响应熵RE）两个不同的值，M熵模块声称可以提供有关患者皮质状态的有用信息，以及镇痛充分程度的间接指标。通常，已经对熵进行了研究，以量化各种GABA能性静脉内麻醉药的麻醉药作用。诱导剂和挥发性麻醉药（如丙泊酚和七氟醚）总体上可与目前的临床金标准双光谱指数（BIS）相提并论。氯胺酮或一氧化二氮给药期间可能无法使用熵引导，因为与患者的意识状态没有可靠的关联。迄今为止，还没有证明RE可以替代疼痛刺激而提高EMG活性。

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