Streptococcus suis type 2 culture supernatant enhances the infection ability of the Swine Influenza virus H3 subtype in MDCK cells

Wang Kaicheng; Lu Chengping

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Streptococcus suis type 2 culture supernatant enhances the infection ability of the Swine Influenza virus H3 subtype in MDCK cells

机译：猪链球菌2型培养物上清液可增强MDCK细胞中猪流感H3亚型的感染能力

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Swine Influenza virus and Streptococcus suis type 2 often occur as a clinical coinfection in pigs, the syndrome of which is more serious than the virus or bacterium sole infection. Streptococcus suis type 2 can produce extracellular proteases, which may cleave hemagglutinin to enhance the infection ability of Swine Influenza virus. The current study investigated whether extracellular proteolytic culture supernatant of Streptococcus suis type 2, isolated from Jiangsu, enhanced the infection ability of H3N2 Swine Influenza virus (A/Swine/Guangdong/4/2003) on MDCK cells. Our data suggested that exposure of MDCK cells to culture supernatant of Streptococcus suis type 2 enhanced the cytopathic effect produced by Swine Influenza virus, hemagglutination of cell culture supernatants and FITC immunofluorescence intensity.

机译：猪流感病毒和猪链球菌2型通常作为临床共同感染发生在猪中，其综合症状比病毒或细菌唯一感染更为严重。猪链球菌2型可产生细胞外蛋白酶，其可裂解血凝素以增强猪流感病毒的感染能力。目前的研究调查了从江苏分离的猪链球菌2型的细胞外蛋白水解培养上清是否增强了H3N2猪流感病毒（A / Swine / Guangdong / 4/2003）对MDCK细胞的感染能力。我们的数据表明，将MDCK细胞暴露于2型猪链球菌培养上清液可增强猪流感病毒产生的细胞病变作用，细胞培养上清液的血凝反应和FITC免疫荧光强度。

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《Berliner und Munchener Tierarztliche Wochenschrift》 |2008年第6期|共5页
作者
Wang Kaicheng; Lu Chengping;
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正文语种 eng
中图分类动物医学（兽医学）;
关键词
cell cytopathic effect;

机译：细胞的细胞病变作用;

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1. Streptococcus suis type 2 culture supernatant enhances the infection ability of the Swine Influenza virus H3 subtype in MDCK cells [J] . Wang Kaicheng, Lu Chengping Berliner und Munchener Tierarztliche Wochenschrift . 2008,第5a6期

机译：猪链球菌2型培养物上清液可增强MDCK细胞中猪流感H3亚型的感染能力
2. Capsular Sialic Acid of Streptococcus suis Serotype 2 Binds to Swine Influenza Virus and Enhances Bacterial Interactions with Virus-Infected Tracheal Epithelial Cells [J] . Yingchao Wang, Carl A. Gagnon, Christian Savard, Infection and immunity . 2013,第12期

机译：猪链球菌血清型2的囊膜唾液酸与猪流感病毒结合并增强与病毒感染的气管上皮细胞的细菌相互作用
3. Human T-cell leukemia virus type-I (HTLV-I) tax is not the only one factor to enhance human immunodeficiency virus type-I (HIV-1) infection in culture-supernatants. [J] . Tempaku A, Maeda Y, Song W, Virus Genes . 2001,第1期

机译：I型人T细胞白血病病毒（HTLV-1）税并不是在培养上清液中增强I型人免疫缺陷病毒（HIV-1）感染的唯一因素。
4. ABILITY OF A BIVALENT SWINE INFLUENZA VACCINE TO PROTECT SWINE AGAINST CHALLENGE WITH SWINE INFLUENZA VIRUS, SUBTYPES HIN1 AND H3N2 [C] . V.J. Rapp-Gabrielson, L.R. Gergen, B.A. Eddy, Congress of the International Pig Veterinary Society . 2000

机译：二价猪流感疫苗的能力保护猪免受猪流感病毒的攻击，亚型Hin1和H3N2
5. Infection with Porcine Reproductive and Respiratory Syndrome Virus and Streptococcus suis changes the pharmacokinetics of ceftiofur hydrochloride in swine. [D] . Day, Deanne N. 2014

机译：猪繁殖与呼吸综合征病毒和猪链球菌感染改变了头孢噻呋盐酸盐在猪中的药代动力学。
6. Capsular Sialic Acid of Streptococcus suis Serotype 2 Binds to Swine Influenza Virus and Enhances Bacterial Interactions with Virus-Infected Tracheal Epithelial Cells [O] . Yingchao Wang, Carl A. Gagnon, Christian Savard, 2013

机译：猪链球菌血清型2的囊膜唾液酸与猪流感病毒结合并增强与病毒感染的气管上皮细胞的细菌相互作用
7. Capsular sialic acid of Streptococcus suis serotype 2 binds to swine influenza virus and enhances bacterial interactions with virus-infected tracheal epithelial cells. [O] . Wang Yingchao, Gagnon Carl A., Savard Christian, 2013

机译：猪链球菌血清型2的荚膜唾液酸结合猪流感病毒并增强与病毒感染的气管上皮细胞的细菌相互作用。

Streptococcus suis type 2 culture supernatant enhances the infection ability of the Swine Influenza virus H3 subtype in MDCK cells

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