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首页> 外文期刊>Fetal and pediatric pathology >Clinical Features of 10 Fetuses With Prenatally Diagnosed Parvovirus B19 Infection and Fetal Hydrops
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Clinical Features of 10 Fetuses With Prenatally Diagnosed Parvovirus B19 Infection and Fetal Hydrops

机译:10例产前诊断为细小病毒B19感染并胎儿积液的胎儿的临床特征

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Objectives: To evaluate the clinical features of fetuses with prenatally diagnosed parvovirus B19 infection and fetal hydrops. Methods: Parvovirus infection was diagnosed by PCR analysis of amniotic fluid or fetal blood. Fetal anemia was assessed by Doppler measurements of the middle cerebral artery peak systolic velocity (MCA-PSV) and confirmed by fetal blood. Intrauterine transfusions (IUT) were performed only if the MCA-PSV was > 1.5 MoM. Results: In our study population 10 cases of parvovirus infection which were associated with fetal hydrops were reviewed. The median gestational age at diagnosis was 21 (16.3-24.2) weeks. Five of our cases received IUT and four fetuses survived. The remaining five cases were managed conservatively and two fetuses survived. Conclusions: The survival rate for parvovirus infection associated with fetal hydrops was 60%. MCA-PSV and IUT are useful for the management and treatment of fetal anemia due to parvovirus infection.
机译:目的:评估具有产前诊断的细小病毒B19感染和胎儿积水的胎儿的临床特征。方法:通过PCR检测羊水或胎儿血液来诊断细小病毒感染。通过多普勒测量大脑中动脉的收缩压峰值速度(MCA-PSV)评估胎儿贫血,并通过胎儿血液进行确认。仅当MCA-PSV> 1.5 MoM时才进行宫内输血(IUT)。结果:在我们的研究人群中,回顾了10例与胎儿积液相关的细小病毒感染。诊断时的中位胎龄为21(16.3-24.2)周。我们有5个病例接受了IUT,有4个胎儿存活。其余5例保守治疗,两名胎儿幸存。结论:与胎儿积液相关的细小病毒感染的存活率为60%。 MCA-PSV和IUT可用于细小病毒感染引起的胎儿贫血的管理和治疗。

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