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HBsAg screening during pregnancy in the French province Picardy

机译：法国皮卡第省怀孕期间的HBsAg筛查

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OBJECTIVE: Screening for maternal hepatitis B surface antigen (HBsAg) is mandatory in France since 1992, however, no evaluation is available. We studied the traceability of HBsAg screening and its prevalence in pregnant women in Picardy for year 2006. PATIENTS AND METHODS: Traceability of HBsAg screening was studied in a sample of 1198 hospital case files, which were randomized and stratified for all the 20 clinics of the region (22,114 deliveries), both public and private. HBsAg prevalence was also studied using various registries (PMSI national database of medical acts performed during hospitalization, central pharmacies and obstetric theatres). RESULTS: The traceability of the screening was lacking in 9.9% (range: 0-34.7%, depending on the maternity clinic). The prevalence of HBsAg during pregnancy was 1.8 per 1000 women (upper limit: 4.3 per 1000) from the case files sample. Registries examination showed large variations of HBsAg's prevalence from 0 to 12.0 per 1000 (mean: 2.9; CI 95%: 7 to 17) among the region. DISCUSSION AND CONCLUSION: HBsAg traceability during pregnancy must be improved. HBsAg prevalence largely varies among maternity clinics and is a significant issue which is underestimated in France.
机译：目的：自1992年以来，法国必须对孕产妇乙型肝炎表面抗原（HBsAg）进行筛查，但目前尚无评估方法。我们研究了2006年皮卡第（Picardy）孕妇的HBsAg筛查的可追溯性及其患病率。病人和方法：对1198例医院病例文件中的HBsAg筛查的可追溯性进行了研究，并对该医院的所有20家诊所进行了随机分组。地区（共22,114架），包括公共和私人区域。还使用各种注册表（住院，中央药房和产科剧院进行的医疗行为的PMSI国家数据库）研究了HBsAg的患病率。结果：筛查的可追溯性不足9.9％（范围：0-34.7％，具体取决于产科诊所）。根据病例档案样本，怀孕期间HBsAg的患病率为每1000名妇女1.8例（上限：每1000名妇女4.3例）。注册表检查显示，该地区的HBsAg流行率从0到12.0 / 1000（平均值：2.9; CI 95％：7到17）有很大差异。讨论与结论：怀孕期间HBsAg的可追溯性必须改善。 HBsAg的患病率在各个产科诊所之间存在很大差异，这是一个重要问题，在法国却被低估了。

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