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首页> 外文期刊>Gerontology: International Journal of Experimental and Clinical Gerontology >Birds do it, bees do it, we do it: Contributions of theoretical modelling to understanding the shape of ageing across the tree of life
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Birds do it, bees do it, we do it: Contributions of theoretical modelling to understanding the shape of ageing across the tree of life

机译:鸟类做到这一点,蜜蜂做到这一点,我们做到这一点:理论模型对理解整个生命树的衰老形状的贡献

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摘要

Organisms of different species age differently. Current theory explains why life should get worse, i.e. why patterns of increasing risk of death should evolve. However, for some species the risk of death remains constant or even falls with advancing age. Evolutionary theory to explain the observed diversity of shapes of ageing is lacking. Theoretical models can provide insights into this diversity. Comparing assumptions of models that find increasing mortality patterns with models that find a variety of patterns, including constant and falling mortality over age, I identify conditions that licence constant or negative shapes of ageing. The results suggest that patterns of improvement and maintenance over age emerge when models potentially allow organisms to (1) escape the 'damage ratchet', (2) achieve maintenance and repair in parallel, (3) face increasing future reproductive potential and (4) incorporate flexible trade-offs. With these insights, theoretical models contribute to hypotheses about which species may follow life history strategies of negligible or negative ageing.
机译:不同物种的生物年龄不同。当前的理论解释了为什么生活会变得更糟,即为什么死亡风险增加的模式应该发展。但是,对于某些物种,死亡的风险保持不变,甚至随着年龄的增长而下降。缺乏解释所观察到的衰老形状多样性的进化论。理论模型可以提供这种多样性的见解。比较发现死亡率增加的模型的假设与发现各种变化的模型(包括随着年龄增长的恒定和下降的死亡率)的假设进行比较,我确定了允许恒定或负向衰老的条件。结果表明,当模型潜在地允许生物体(1)逃脱“损害棘轮”,(2)同时实现维护和修复,(3)面对未来生殖潜力增加和(4)时,就会出现随着年龄增长而改善和维持的模式。结合灵活的权衡。有了这些见解,理论模型就有助于假设哪些物种可能遵循可忽略的或不利的衰老的生活史策略。

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