Randomized trials of PCIs versus CABG surgery: Why coronary stenting should remain the first choice of revascularization in non-diabetic patients and why the controversy is still present in diabetics

RodríguezA.E.; ArismendiL.; RomeroG.; Rodríguez-GranilloA.M.

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Randomized trials of PCIs versus CABG surgery: Why coronary stenting should remain the first choice of revascularization in non-diabetic patients and why the controversy is still present in diabetics

机译：PCIs与CABG手术的随机试验：为什么在非糖尿病患者中冠状动脉支架置入术仍应是血运重建的首选，为什么在糖尿病患者中仍然存在争议

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Knowing the best revascularization option for diabetic patients with multiple vessel disease is a challenge without a definitive answer. There have been several randomized clinical trials and subsequent meta-analyses comparing current available technology trying to reach an exhaustive conclusion; comparisons between coronary artery bypass grafts and bare-metal stents, coronary artery bypass grafts and first generation drug-eluting stents and, most recently, first generation versus latest generation drug-eluting stents generated some interesting results. Information provided by pooled data from some of the most important randomized clinical cardiology trials from the last two decades have produced surprising results. The authors analyze these data to discuss the best therapeutic procedures for each patient.

机译：没有确定的答案，要知道患有多支血管疾病的糖尿病患者的最佳血运重建方案是一个挑战。已经有几项随机临床试验和随后的荟萃分析比较了试图得出详尽结论的当前可用技术。比较冠状动脉旁路移植物和裸金属支架，冠状动脉旁路移植物和第一代药物洗脱支架，以及最近的第一代与最新一代药物洗脱支架，产生了一些有趣的结果。最近二十年来一些最重要的随机临床心脏病学试验的汇总数据提供的信息产生了令人惊讶的结果。作者分析了这些数据，以讨论针对每个患者的最佳治疗程序。

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《Expert review of cardiovascular therapy》 |2014年第3期|共13页
作者
RodríguezA.E.; ArismendiL.; RomeroG.; Rodríguez-GranilloA.M.;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
bare metal stents; coronary artery bypass surgery; coronary artery disease; drug-eluting stents; graft closure; randomized trials; restenosis; stent thrombosis; stents;

机译：裸金属支架;冠状动脉搭桥手术;冠状动脉疾病;药物洗脱支架;移植物闭合;随机试验;再狭窄;支架血栓形成;支架;

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1. Randomized trials of PCIs versus CABG surgery: Why coronary stenting should remain the first choice of revascularization in non-diabetic patients and why the controversy is still present in diabetics [J] . RodríguezA.E., ArismendiL., RomeroG., Expert review of cardiovascular therapy . 2014,第3期

机译：PCIs与CABG手术的随机试验：为什么在非糖尿病患者中冠状动脉支架置入术仍应是血运重建的首选，为什么在糖尿病患者中仍然存在争议
2. Coronary artery bypass surgery versus percutaneous coronary intervention with stent implantation in patients with multivessel coronary artery disease (the Stent or Surgery trial): a randomised controlled trial. [J] . Stables R The Lancet . 2002,第9338期

机译：多支冠状动脉疾病患者的冠状动脉搭桥手术与经皮冠状动脉支架置入术（支架或手术试验）：一项随机对照试验。
3. Randomized, controlled trial of coronary artery bypass surgery versus percutaneous coronary intervention in patients with multivessel coronary artery disease: six-year follow-up from the Stent or Surgery Trial (SoS). [J] . Booth J, Clayton T, Pepper J, Circulation: An Official Journal of the American Heart Association . 2008,第4期

机译：多支冠状动脉疾病患者冠状动脉搭桥手术与经皮冠状动脉介入治疗的随机对照试验：支架或手术试验（SoS）的六年随访。
4. Monocyte chemotactic protein-1 and E-selectin inflammatory patterns in coronary artery bypass graft surgery with the miniaturized extracorporeal circulation: a randomized clinical trial [C] . Mariani S., Formica F., Broccolo F., International Congress on Coronary Artery Disease. . 2013

机译：单核细胞趋化蛋白-1和冠状动脉旁路移植手术中的e-Selectin炎性模式，具有小型化体外循环：随机临床试验
5. Meta-analysis: The impact of thrombectomy during PCI (percutaneous coronary intervention) on mortality, re-infarction and target vessel revascularization among patients with ST elevation myocardial infarction compared with standard PCI. [D] . Martar, Martar. 2016

机译：荟萃分析：与标准PCI相比，ST抬高型心肌梗死患者在PCI（经皮冠状动脉介入治疗）期间进行血栓切除术对死亡率，再梗塞和靶血管血运重建的影响。
6. Randomized Clinical Trial of Surgical vs. Percutaneous vs. Hybrid Revascularization in Multivessel Coronary Artery Disease: Residual Myocardial Ischemia and Clinical Outcomes at One Year—Hybrid coronary REvascularization Versus Stenting or Surgery (HREVS) [O] . Vladimir Ganyukov, Nikita Kochergin, Aleksandr Shilov, 2020

机译：多支冠状动脉疾病的手术经皮或混合血运重建的随机临床试验：残存的心肌缺血和一年的临床结果—混合冠状动脉血运重建与支架或手术（HREVS）
7. Geographical Difference of the Interaction of Sex With Treatment Strategy in Patients With Multivessel Disease and Left Main Disease: A Meta-Analysis From SYNTAX (Synergy Between PCI With Taxus and Cardiac Surgery), PRECOMBAT (Bypass Surgery Versus Angioplasty Using Sirolimus-Eluting Stent in Patients With Left Main Coronary Artery Disease), and BEST (Bypass Surgery and Everolimus-Eluting Stent Implantation in the Treatment of Patients With Multivessel Coronary Artery Disease) Randomized Controlled Trials [O] . Sotomi, Yohei, Onuma, Yoshinobu, Cavalcante, Rafael, 2017

机译：多支血管疾病和左主干疾病患者性别与治疗策略相互作用的地域差异：荟萃分析：SYNTAX（紫杉醇与心脏手术的PCI协同作用），PRECOMBAT（使用西罗莫司洗脱支架进行的搭桥手术与血管成形术）伴有左主干冠状动脉疾病）和BEST（绕过手术和依维莫司洗脱支架植入治疗多支血管冠状动脉疾病的患者）随机对照试验

Randomized trials of PCIs versus CABG surgery: Why coronary stenting should remain the first choice of revascularization in non-diabetic patients and why the controversy is still present in diabetics

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