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The clinical management of inoperable endometrial carcinoma

机译:不可手术子宫内膜癌的临床治疗

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摘要

Unresectable endometrial cancer, while rare, has a very poor prognosis, with a survival rate of 2 to 8 months. Although endometrial cancer is generally regarded as a survivable disease, the less common advanced and aggressive forms account for a large portion of endometrial cancer related deaths. Given the paucity of inoperable disease, randomized clinical data is lacking in this specific patient population. Management decisions regarding radiation therapy or systemic therapy are largely guided by the existing data in the setting of recurrence or second-line treatment, adjuvant therapy following optimal debulking, or in patients who are considered inoperable due to medical comorbidities rather than the extent of their disease.
机译:不可切除的子宫内膜癌虽然很少见,但预后很差,生存期为2至8个月。尽管子宫内膜癌通常被认为是可生存的疾病,但较不常见的晚期和侵袭性形式占子宫内膜癌相关死亡的很大一部分。鉴于无法手术的疾病很少,在这种特定的患者人群中缺乏随机的临床数据。有关放射疗法或全身疗法的管理决策在很大程度上取决于现有数据,包括复发或二线治疗,最佳减量化后的辅助疗法或因医疗合并症而不是疾病程度而无法手术的患者。

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