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首页> 外文期刊>Fish & Shellfish Immunology >Effects of four anaesthetics on the innate immune response of gilthead seabream (Sparus aurata L.)
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Effects of four anaesthetics on the innate immune response of gilthead seabream (Sparus aurata L.)

机译:四种麻醉剂对金头鲷(Sparus aurata L.)的先天免疫反应的影响

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摘要

Anaesthesia may depress the immune system in mammals, but there is no available information on this topic in fish. In the present work, four anaesthetics that are used in aquaculture, MS222 (0(.)19 mM), benzocaine (0(.)21 mM), 2-phenoxyethanol (1(.)6 mM) and quinaldine sulphate (0(.)083 mM), were tested in order to observe their effects on the gilthead seabream (Sparus aurata L.) innate immune system. The results showed that the four anaesthetics produced increased blood glucose levels after an hour. In addition, benzocaine and 2-phenoxyethanol depressed complement activity and phagocytosis, while MS222 and quinaldine sulphate did not. Some anaesthesia is a common practice in aquaculture, the data obtained should be taken into account to avoid possible immunodepression in farmed fish.
机译:麻醉可能会降低哺乳动物的免疫系统,但目前尚无有关鱼类中该主题的信息。在本工作中,水产养殖中使用了四种麻醉剂,MS222(0(。)19 mM),苯佐卡因(0(。)21 mM),2-苯氧乙醇(1(。)6 mM)和硫酸奎尼丁(0(测试了083 mM),以观察它们对金头鲷(Sparus aurata L.)先天免疫系统的影响。结果表明,四种麻醉剂在一小时后产生了较高的血糖水平。此外,苯佐卡因和2-苯氧基乙醇抑制补体活性和吞噬作用,而MS222和奎尼丁硫酸盐则没有。某些麻醉是水产养殖中的一种常见做法,应将获得的数据考虑在内,以避免养殖鱼类可能出现免疫抑制。

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