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首页> 外文期刊>Canadian Journal of Physiology and Pharmacology >Mechanical plasticity and contractile properties of airway smooth muscle.
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Mechanical plasticity and contractile properties of airway smooth muscle.

机译:气道平滑肌的机械可塑性和收缩特性。

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摘要

Smooth muscle has the unique ability to adapt easily and quickly to length changes without compromising its ability to generate force. This ability is referred to as mechanical plasticity and is now considered to be an important aspect of smooth muscle that affects both its contractile and relaxation behaviour. It is therefore important to incorporate knowledge of plasticity into further studies of smooth muscle behaviour. It is also important that future studies be focused on deciphering the mechanism of smooth muscle length adaptation and plasticity. This review outlines some of the proposed mechanisms determining plasticity. However, it should be said that there are other proposed mechanisms not touched upon here, which may be equally as important. This review also focuses on the relevance of smooth muscle plasticity in asthma, but it is important to remember that there are other places where smooth muscle plasticity may play an equally important role.
机译:平滑肌具有独特的能力,可以轻松快速地适应长度变化,而不会影响其产生力的能力。这种能力被称为机械可塑性,现在被认为是影响其收缩和放松行为的平滑肌的重要方面。因此,重要的是将可塑性知识纳入对平滑肌行为的进一步研究中。同样重要的是,未来的研究应集中在解读平滑肌长度适应性和可塑性的机制上。这篇综述概述了确定可塑性的一些拟议机制。但是,应该说这里还没有涉及其他提议的机制,它们可能同样重要。这篇综述也侧重于哮喘中平滑肌可塑性的相关性,但重要的是要记住,在其他地方平滑肌可塑性可能起着同等重要的作用。

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