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首页> 外文期刊>Canadian Journal of Physiology and Pharmacology >Management of oxidative stress by microalgae
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Management of oxidative stress by microalgae

机译：微藻对氧化应激的控制

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摘要

The aim of this review is to provide an overview of the current research on oxidative stress in eukaryotic microalgae and the antioxidant compounds microalgae utilize to control oxidative stress. With the potential to exploit microalgae for the large-scale production of antioxidants, interest in how microalgae manage oxidative stress is growing. Microalgae can experience increased levels of oxidative stress and toxicity as a result of environmental conditions, metals, and chemicals. The defence mechanisms for microalgae include antioxidant enzymes such as superoxide dismutase, catalase, peroxidases, and glutathione reductase, as well as non-enzymatic antioxidant molecules such as phytochelatins, pigments, polysaccharides, and polyphenols. Discussed herein are the 3 areas the literature has focused on, including how conditions stress microalgae and how microalgae respond to oxidative stress by managing reactive oxygen species. The third area is how beneficial microalgae antioxidants are when administered to cancerous mammalian cells or to rodents experiencing oxidative stress.
机译：这篇综述的目的是提供对目前在真核微藻中的氧化应激和微藻用于控制氧化应激的抗氧化剂化合物的研究的概述。随着利用微藻大规模生产抗氧化剂的潜力，对微藻如何管理氧化应激的兴趣日益增长。由于环境条件，金属和化学物质的影响，微藻可能会经历更高水平的氧化应激和毒性反应。微藻的防御机制包括抗氧化酶，例如超氧化物歧化酶，过氧化氢酶，过氧化物酶和谷胱甘肽还原酶，以及非酶抗氧化分子，例如植物螯合素，色素，多糖和多酚。本文讨论的是文献所关注的3个领域，包括条件如何对微藻产生压力以及微藻如何通过管理活性氧来响应氧化应激。第三个领域是微藻抗氧化剂在施予癌性哺乳动物细胞或遭受氧化应激的啮齿类动物时的有益效果。

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