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首页> 外文期刊>Canadian Journal of Physiology and Pharmacology >Investigating the autonomic nervous system and cognitive functions as potential mediators of an association between cardiovascular disease and driving performance
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Investigating the autonomic nervous system and cognitive functions as potential mediators of an association between cardiovascular disease and driving performance

机译：研究自主神经系统和认知功能是心血管疾病与驾驶表现之间潜在关联的媒介

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摘要

Cardiovascular disease (CVD) impacts the autonomic nervous system and cognitive functions related to activities of daily living, including driving an automobile. Although CVD has been linked to unsafe driving, mechanisms underlying this relationship remain elusive. The aim of this study was to examine the role of cognitive functions and the autonomic nervous system as potential mediators of driving performance. Nineteen individuals having recently suffered a cardiac event and 16 individuals with no history of CVD completed a simulated drive using a STISIM simulator to assess driving performance. Heart rate was recorded throughout testing using a Polar RS800CX heart rate monitor, and measures of executive, orienting, and alerting functions were obtained through the Attention Network Test. We used the Baron and Kenny analysis method to assess potential mediating effects of the relationship between CVD and driving performance. Executive function was the only potential mediator investigated to be associated with driving (p < 0.01) and CVD (p < 0.05); however, it did not appear to play a mediating role (p = 0.28). These results suggest that individuals with CVD exhibit decrements in complex cognitive tasks such as driving and that further research is needed to better understand the mechanisms underlying this relationship.
机译：心血管疾病（CVD）影响与日常生活活动有关的植物神经系统和认知功能，包括驾驶汽车。尽管CVD与不安全驾驶有关，但这种关系所依据的机制仍然难以捉摸。这项研究的目的是检查认知功能和自主神经系统作为驾驶表现的潜在介体的作用。最近有19个人经历过心脏事件，有16个人没有CVD病史，使用STISIM仿真器评估驾驶性能完成了模拟驾驶。使用Polar RS800CX心率监测器在整个测试过程中记录心率，并通过“注意网络测试”获得执行，定向和警报功能的度量。我们使用Baron和Kenny分析方法评估CVD与驾驶性能之间关系的潜在中介作用。执行功能是研究中唯一与驾驶（p <0.01）和CVD（p <0.05）相关的潜在介体。但是，它似乎没有起到中介作用（p = 0.28）。这些结果表明，患有CVD的个体在诸如驾驶等复杂的认知任务中表现出下降，需要进一步研究以更好地理解这种关系的潜在机制。

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