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首页> 外文期刊>Canadian Journal of Physiology and Pharmacology >Factors controlling ovarian apoptosis.
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Factors controlling ovarian apoptosis.

机译:控制卵巢细胞凋亡的因素。

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摘要

Apoptosis is a form of programmed cell death that is essential for the development of the embryo and adult tissue plasticity. In adults, it is observed mainly in those tissues undergoing active differentiation such as the hematopoietic system, testis, ovary, and intestinal epithelium. Apoptosis can be triggered by many factors, such as hormones, cytokines, and drugs, depending on the type of the cell. While the intracellular signaling mechanisms may vary in different cells, they all display similar morphological and biochemical features at the later stages of the apoptotic process. This review focuses on the factors controlling ovarian apoptosis, emphasizing observations made on GnRH-induced apoptotic process in goldfish follicles.
机译:凋亡是程序性细胞死亡的一种形式,对胚胎的发育和成年组织的可塑性至关重要。在成人中,主要在经历活跃分化的组织(例如造血系统,睾丸,卵巢和肠上皮)中观察到。细胞凋亡可以由多种因素触发,例如激素,细胞因子和药物,取决于细胞的类型。虽然细胞内信号转导机制在不同细胞中可能有所不同,但它们在凋亡过程的后期均表现出相似的形态和生化特征。这篇综述着重于控制卵巢细胞凋亡的因素,强调对GnRH诱导的金鱼卵泡凋亡过程的观察。

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