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首页> 外文期刊>Fisheries and Aquatic Sciences >Synergistic Effects of Dietary Vitamins C and E onMethyl mercury-Induced Toxicity in Juvenile Olive FlounderParalichthys olivaceus
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Synergistic Effects of Dietary Vitamins C and E onMethyl mercury-Induced Toxicity in Juvenile Olive FlounderParalichthys olivaceus

机译：饮食中维生素C和E对甲基汞诱导的幼橄榄比目鱼的毒性的协同作用

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摘要

This experiment was conducted to evaluate the synergistic effects of vitamin C and E on methylmercury (MeHg) toxicity in juvenile olive flounder Paralichthys olivaceus. In a 3*3 factorial design, 9 experimental diets containing three different vitaminC (0, 200 or 400 mg/kg diet in the form of l-ascorbyl-2-monophosphate) and vitamin E (0, 100 or 200 mg/kg diet in the form of dl-a-tocopheryl acetate) levels with the Hg toxicity level (20 mg/kg diet in the form of MeHg). Triplicate groups of fish averaging 2.3 ± 0.05 g (mean ± SD) were fed one of the 9 diets in a flow through system for 8 weeks. Fish fed 400 mg vitamin C/kg diet with 100 or 200 mg vitamin E/kg diet showed significantly (P < 0.05) higher weight gain (WG) than did fish fed the other diets. Fish fed 400 mg vitamin C/kg diet at all vitamin E levels and those which fed vitamin C and E equally at a rate of 200 mg/kg diet showed significantly (P < 0.05) higher feed efficiency (FE), specific growth rate (SGR) and protein efficiency ratio (PER) than did fish fed the other diets. Fish fed 200 and 400 mg vitamin C/kg diet exhibited significantly (P < 0.05) lower Hg concentration in their muscle as well as kidney than did fish fed the other diets. Therefore, these results clearly indicated that the synergistic effects of these two vitamins on MeHg toxicity by supplementing dietary vitamin C (200 and 400 mg/kg diet) with vitamin E (100 and 200 mg/kg diet) in juvenile olive flounder.
机译：进行该实验以评估维生素C和E对少年橄榄比目鱼Paralichthys olivaceus中甲基汞（MeHg）毒性的协同作用。在3 * 3因子设计中，有9种实验饮食包含三种不同的维生素C（0、200或400 mg / kg饮食，形式为1-抗坏血酸-2-单磷酸酯）和维生素E（0、100或200 mg / kg饮食） （以dl-α-生育酚乙酸酯的形式）和Hg毒性水平（以MeHg形式的20 mg / kg饮食）。将三组平均2.3±0.05 g（平均值±SD）的鱼在流通系统中喂食9种日粮之一。饲喂400 mg维生素C / kg饲料和100或200 mg维生素E / kg饲料的鱼，体重增加（WG）显着（P <0.05），高于饲喂其他饲料的鱼。在所有维生素E水平下饲喂400 mg维生素C / kg饲料的鱼和以200 mg / kg饲喂相同剂量的维生素C和E的鱼显示出显着（P <0.05）高饲料效率（FE）和特定生长率（ SGR）和蛋白质效率比（PER）高于其他饲料喂养的鱼类。饲喂200和400 mg维生素C / kg饲料的鱼，其肌肉和肾脏中的Hg浓度显着低于饲喂其他饮食的鱼（P <0.05）。因此，这些结果清楚地表明，在少年比目鱼中，通过在饮食维生素C（200和400 mg / kg饮食）中添加维生素E（100和200 mg / kg饮食）来补充这两种维生素对MeHg毒性的协同作用。

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