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Airborne Aspergillus fumigatus conidia: a risk factor for aspergillosis.

机译:空气传播的烟曲霉分生孢子:曲霉病的危险因素。

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Aspergillus fumigatus is an opportunistic fungal pathogen that causes invasive aspergillosis, a usually fatal infection. The disease has risen in prominence in recent years due to the increasing numbers of severely immunocompromised patients becoming infected. The fungus is ubiquitous in the environment, producing large numbers of conidia that are dispersed in the air. Humans inhale numerous conidia everyday, but infections are not seen in healthy individuals. As inhalation of conidia is the main route of infection, considerable efforts are required to prevent infection in susceptible patients. This review summarises the current knowledge on airborne concentrations of A. fumigatus conidia, their background levels in outdoor air and seasonal distribution patterns. New and established methods of air sampling for airborne A. fumigatus conidia are discussed. Common environmental sources of the fungus are reviewed, including its presence in compost heaps. Finally, the lack of stringent guidelines on the monitoring and control of airborne A. fumigatus concentrations in hospitals is discussed.Digital Object Identifier http://dx.doi.org/10.1016/j.fbr.2011.07.002
机译:烟曲霉是一种机会性真菌病原体,可引起侵袭性曲霉病,这通常是致命的感染。近年来,由于越来越多的严重免疫功能低下的患者被感染,这种疾病的发病率在上升。该真菌在环境中无处不在,产生大量散布在空气中的分生孢子。人类每天吸入大量分生孢子,但在健康个体中未见感染。由于吸入分生孢子是感染的主要途径,因此需要做出很大的努力来防止易感患者感染。这篇综述总结了目前有关空气中iA浓度的知识。烟的分生孢子,它们在室外空气中的背景水平和季节性分布模式。机载 A空气采样的新方法和已建立的方法。讨论了烟熏分生孢子。审查了真菌的常见环境来源,包括其在堆肥中的存在。最后,缺乏对机载A的监视和控制的严格指南。讨论了医院中的烟气浓度。数字对象标识符http://dx.doi.org/10.1016/j.fbr.2011.07.002

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