• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Fungal Biology Reviews >Antifungal peptides come of age
【24h】

Antifungal peptides come of age

机译：抗真菌肽成年

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Plants, vertebrate and invertebrate animals, and even fungi produce a broad range of antimicrobial peptides that exhibit potent cytotoxic activity against a broad-spectrum of fungi and thus serve as host defence molecules. They are major components of the innate immune defence arsenal of these organisms against a wide range of fungal pathogens. A rich diversity of antifungal peptides exists, and the same peptide sequence is rarely found from two closely related plant or animal species. Because of their potent antifungal activity, there has been a great deal of interest in exploiting these peptides as commercial antifungal agents in agriculture as well as medicine. In fact, significant research has been carried out to develop these naturally occurring antifungal peptides as therapeutic agents against microbial infections. Furthermore, small chemically synthesized antifungal peptides have been generated and their structure–activity relationships as well as mechanisms of antifungal action have been extensively investigated.
机译：植物，脊椎动物和无脊椎动物，甚至真菌产生多种抗菌肽，这些肽对广谱真菌表现出有效的细胞毒活性，因此可作为宿主防御分子。它们是这些生物体针对各种真菌病原体的先天免疫防御武库的主要组成部分。存在大量的抗真菌肽，并且从两个密切相关的动植物物种中很少发现相同的肽序列。由于它们具有强大的抗真菌活性，因此人们对将这些肽用作农业和医学中的商业抗真菌剂有着极大的兴趣。实际上，已经进行了大量研究以开发这些天然存在的抗真菌肽作为抗微生物感染的治疗剂。此外，已经产生了小的化学合成的抗真菌肽，并且已经广泛研究了它们的结构-活性关系以及抗真菌作用的机理。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号