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Antimicrobial Agent-Containing Polymeric Materials

机译:含抗菌剂的高分子材料

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Crosslinked poly(methyl methacrylate/ethylene glycol dimethacrylate) P(MMA/EGDMA) nanoparticles (NPs) loaded with the antimicrobial agent methyl paraben (MP) were prepared by miniemulsion polymerization. The MP-loaded NPs (i.e., ≤9.63 wt% MP) had an average size in the range of 108 to 145 nm. The NPs were subsequently incorporated in a low-density polyethylene (LDPE) matrix, in the form of individual NPs and small aggregates ({L-End} <1 μm), employing a twin screw extrusion process in the presence and absence of appropriate compatibilizers (i.e., montmorillonite clay (MMT), mesoporous silica (MCM-41)). MP exhibited a sustained release profile from the P(MMA/EGDMA) (NPs) as well as from the LDPE matrix.
机译:通过微乳液聚合制备了负载有抗菌剂对羟基苯甲酸甲酯(MP)的交联聚(甲基丙烯酸甲酯/乙二醇二甲基丙烯酸甲酯)P(MMA / EGDMA)纳米颗粒(NPs)。载有MP的NP(MP≤9.63 wt%)的平均粒径为108至145 nm。随后,在存在和不存在适当增容剂的情况下,采用双螺杆挤出工艺将NP以单个NP和小聚集体({L-End} <1μm)的形式掺入低密度聚乙烯(LDPE)基质中(即蒙脱土(MMT),中孔二氧化硅(MCM-41))。 MP表现出从P(MMA / EGDMA)(NP)以及LDPE基质的持续释放特性。

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