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Multi-component kinetic modeling for controlling local compositions in thermosensitive polymers

机译:用于控制热敏聚合物中局部成分的多组分动力学建模

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摘要

An explicit terminal copolymerization kinetic model accounting for the copolymerization of up to four different comonomers is developed and applied to model the conversion profiles and local compositional gradients in functionalized PNIPAM-based polymer and hydrogel systems. The kinetics of the functional comonomer(s) have a large influence on both the mole fraction and chain distribution of functional groups in polymers. Strategies are developed to synthesize polymers with uniform compositions by applying semi-batch techniques or via copolymerization of multiple monomers with the same target functionality but with divergent reactivities relative to NIPAM. Synthetic protocols are also designed to maximize the compositional uniformity and randomness of ampholytic polymers.
机译:建立了一个明确的末端共聚动力学模型,该模型考虑了多达四种不同的共聚单体的共聚反应,并将其用于模拟功能化PNIPAM基聚合物和水凝胶体系中的转化曲线和局部组成梯度。官能共聚单体的动力学对聚合物中官能团的摩尔分数和链分布都具有很大的影响。通过应用半间歇技术或通过具有相同目标官能度但相对于NIPAM具有不同反应性的多种单体的共聚,已开发出策略来合成具有均一组成的聚合物。还设计了合成方案以使两性聚合物的组成均匀性和无规性最大化。

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