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首页> 外文期刊>Magnetic resonance in medicine: official journal of the Society of Magnetic Resonance in Medicine >High-field diffusion MR histology: image-based correction of eddy-current ghosts in diffusion-weighted rapid acquisition with relaxation enhancement (DW-RARE).
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High-field diffusion MR histology: image-based correction of eddy-current ghosts in diffusion-weighted rapid acquisition with relaxation enhancement (DW-RARE).

机译：高场扩散MR组织学：对基于扩散的加权快速采集中具有松弛增强（DW-RARE）的涡流重影进行基于图像的校正。

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摘要

High-resolution, diffusion-weighted (DW) MR microscopy is gaining increasing acceptance as a nondestructive histological tool for the study of fixed tissue samples. Spin-echo sequences are popular for high-field diffusion imaging due to their high tolerance to B(0) field inhomogeneities. Volumetric DW rapid acquisition with relaxation enhancement (DW-RARE) currently offers the best tradeoff between imaging efficiency and image quality, but is relatively sensitive to residual eddy-current effects on the echo train phase, resulting in encoding direction-dependent ghosting in the DW images. We introduce two efficient, image-based phase corrections for ghost artifact reduction in DW-RARE of fixed tissue samples, neither of which require navigator echo acquisition. Both methods rely on the phase difference in k-space between the unweighted reference image and a given DW image and assume a constant, per-echo phase error arising from residual eddy-current effects in the absence of sample motion. Significant qualitative and quantitative ghost artifact reductions are demonstrated for individual DW and calculated diffusion tensor images.
机译：高分辨率，弥散加权（DW）MR显微镜作为一种用于研究固定组织样本的非破坏性组织学工具，其接受度越来越高。自旋回波序列因其对B（0）场非均匀性的高耐受性而在高场扩散成像中很受欢迎。目前，具有弛豫增强功能的体积DW快速采集（DW-RARE）在成像效率和图像质量之间提供了最佳折衷，但对回波序列相位上的残留涡流效应相对敏感，从而导致DW中编码方向相关的重影图片。我们介绍了两个有效的基于图像的相位校正，用于减少固定组织样本的DW-RARE中的​​幻影伪影，这两种校正均不需要导航回波采集。两种方法都依赖于未加权参考图像和给定DW图像之间k空间中的相位差，并假设在没有样本运动的情况下，由于残留涡流效应而产生的恒定的每个回波相位误差。对于单个DW和计算得出的扩散张量图像，证明了明显的定性和定量重影伪影减少。

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