...
首页> 外文期刊>Biochemistry >Dynamics of Formation of Lysoforms on Enzymatic Hydrolysis of PHosphatidylalkanols
【24h】

Dynamics of Formation of Lysoforms on Enzymatic Hydrolysis of PHosphatidylalkanols

机译:磷脂酰链烷醇的酶水解过程中溶菌形式的形成动力学

获取原文
获取原文并翻译 | 示例
           

摘要

Hydrolysis of 1,2-dioleoyl-sn-glycero-3-phosphomethanol (DOPM), 1,2-dioleoyl-sn-glycero-3-phosphoethanol (DOPEt), 1,2-dioleoyl-sn-glycero-3-phosphethyleneglycol (DOPEG), and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) catalyzed by phospholipase A_2 (PLA_2) from porcine pancreas was studied in single-component and binary model bilayer membranes (liposomes). The presence of anionic phosphatidylalkanols increases the rate of hydrolysis of zwitterionic DOPC in liposomes by the action of PLA_2. The rate of formation of lysoforms of anionic ("acidic") lipids at the initial reaction stage in single-component liposomes increased in the following sequence: DOPEG
机译:1,2-二油酰基-sn-甘油-3-磷酸乙醇(DOPM),1,2-二油酰基-sn-甘油-3-磷酸乙醇(DOPEt),1,2-二油酰基-sn-甘油-3-磷酸乙二醇的水解(在单组分和二元模型双层膜(脂质体)中,研究了猪胰磷脂酶A_2(PLA_2)催化的1,2-二油酰基-sn-甘油-3-磷酸胆碱(DOPC)。阴离子磷脂酰链烷醇的存在通过PLA_2的作用提高了脂质体中两性离子DOPC的水解速率。在单组分脂质体的初始反应阶段,阴离子(“酸性”)脂质的溶菌型形成速率按以下顺序增加:DOPEG

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号