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首页> 外文期刊>Cancer epidemiology >Occupational and recreational physical activity during adult life and the risk of cancer among men.
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Occupational and recreational physical activity during adult life and the risk of cancer among men.

机译:成人生活中的职业和娱乐活动以及男性患癌症的风险。

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BACKGROUND: There is a strong evidence for a protective role of physical activity (PA) on cancers of the colon, breast (postmenopausal) and endometrium, but data are less consistent or scarce for other cancer types. This study assessed the relationship between occupational and recreational PA and cancer risk among men in a population-based case-control study conducted in Montreal, Canada. METHODS: Incident cases of cancer of the lung (n=857), colon (n=496), bladder (n=484), prostate (n=449), stomach (n=251), rectum (n=248), non-Hodgkin's lymphoma (n=215), kidney (n=177), pancreas (n=116), melanoma (n=103), esophagus (n=99), Hodgkin's lymphoma (n=54), and 533 population controls, were interviewed. Detailed lifetime occupational PAs were translated into metabolic equivalents. Participation in sports and outdoor activities was elicited. RESULTS: Compared to those with low lifetime occupational PA levels, men with high occupational PA levels had decreased odds ratios (OR) for all cancer types. The strongest evidence was for cancers of the colon [OR: 0.58, 95% confidence interval (CI): 0.34-0.99] and the prostate (OR: 0.54, 95% CI: 0.31-0.95). Men engaging in sports and outdoor activities had lower risks of lung (OR: 0.69, 95% CI: 0.52-0.91), esophageal (OR: 0.54, 95% CI: 0.30-0.97) and bladder (OR: 0.78, 95% CI: 0.59-1.05) cancers, and somewhat increased risks of melanoma (OR: 1.24, 95% CI: 0.73-2.12). CONCLUSIONS: A protective effect of high lifetime occupational PA levels was observed for colon and prostate cancers. A tendency for inverse associations was also noted for several other cancer types. Recreational PA was inversely related with smoking-related cancers including lung, esophageal and bladder cancers.
机译:背景:有充分的证据表明,体育锻炼(PA)对结肠癌,乳腺癌(绝经后)和子宫内膜癌具有保护作用,但其他癌症类型的数据不一致或缺乏。这项研究在加拿大蒙特利尔进行的一项基于人群的病例对照研究中,评估了职业和娱乐性PA与男性癌症风险之间的关系。方法:肺癌(n = 857),结肠(n = 496),膀胱(n = 484),前列腺(n = 449),胃(n = 251),直肠(n = 248),非霍奇金淋巴瘤(n = 215),肾脏(n = 177),胰腺(n = 116),黑素瘤(n = 103),食道(n = 99),霍奇金淋巴瘤(n = 54)和533个人群对照,接受了采访。详细的终生职业PA被转换为代谢当量。引起了参加运动和户外活动。结果:与那些终生职业性PA水平较低的男性相比,职业性PA水平较高的男性在所有癌症类型中的优势比(OR)均降低。最有力的证据是结肠癌[OR:0.58,95%置信区间(CI):0.34-0.99]和前列腺癌(OR:0.54,95%CI:0.31-0.95)。从事运动和户外活动的男性患肺癌(OR:0.69,95%CI:0.52-0.91),食道癌(OR:0.54,95%CI:0.30-0.97)和膀胱(OR:0.78,95%CI)的风险较低:0.59-1.05),并且黑色素瘤的风险有所增加(或:1.24,95%CI:0.73-2.12)。结论:观察到高职业性PA水平对结肠癌和前列腺癌具有保护作用。还指出了其他几种癌症类型的反向关联趋势。娱乐性PA与吸烟相关癌症(包括肺癌,食道癌和膀胱癌)呈负相关。

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