A prospective study of soluble receptor for advanced glycation end-products and colorectal cancer risk in postmenopausal women

Chen Liang; Duan Zhigang; Tinker Lesley; Sangi-Haghpeykar Haleh; Strickler Howard; Ho Gloria Y. F.; Gunter Marc J.; Rohan Thomas; Logsdon Craig; White Donna L.; Royse Kathryn; El-Serag Hashem B.; Jiaoa Li

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A prospective study of soluble receptor for advanced glycation end-products and colorectal cancer risk in postmenopausal women

机译：可溶性受体对绝经后妇女晚期糖基化终产物和大肠癌风险的前瞻性研究

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Objectives: Receptor for advanced glycation end products (RAGE) expressed on adipocytes and immune cells can bind to ligand Ne-(carboxymethyl)-lysine (CML) and trigger dysregulation of adipokines and chronic inflammation. Soluble RAGE (sRAGE) mitigates the detrimental effect of RAGE. We examined the associations between circulating levels of CML-AGE and sRAGE and colorectal cancer (CRC).

机译：目的：在脂肪细胞和免疫细胞上表达的晚期糖基化终产物（RAGE）的受体可与配体Ne-（羧甲基）-赖氨酸（CML）结合，并引发脂肪因子失调和慢性炎症。可溶性RAGE（sRAGE）减轻了RAGE的有害影响。我们检查了CML-AGE和sRAGE的循环水平与结直肠癌（CRC）之间的关联。

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《Cancer epidemiology》 |2016年第null期|共9页
作者
Chen Liang; Duan Zhigang; Tinker Lesley; Sangi-Haghpeykar Haleh; Strickler Howard; Ho Gloria Y. F.; Gunter Marc J.; Rohan Thomas; Logsdon Craig; White Donna L.; Royse Kathryn; El-Serag Hashem B.; Jiaoa Li;
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正文语种 eng
中图分类肿瘤学;
关键词
Colorectal cancer; Advanced glycation end-products; Receptor for advanced glycosylation end-products; Epidemiology; sRAGE; Body weight; Obesity; N-epsilon-(carboxymethyl)-lysine; Pattern recognition receptors;

机译：大肠癌;晚期糖基化终产物;晚期糖基化终产物的受体;流行病学;sRAGE;体重;肥胖;N-ε-（羧甲基）-赖氨酸;模式识别受体;

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1. A prospective study of soluble receptor for advanced glycation end-products and colorectal cancer risk in postmenopausal women [J] . Chen Liang, Duan Zhigang, Tinker Lesley, Cancer epidemiology . 2016,第Null期

机译：可溶性受体对绝经后妇女晚期糖基化终产物和大肠癌风险的前瞻性研究
2. Correlation among soluble receptors for advanced glycation end-products, soluble vascular adhesion protein-1/semicarbazide-sensitive amine oxidase (sVAP-1) and cardiometabolic risk markers in apparently healthy adolescents: a cross-sectional study [J] . Gurecka Radana, Koborova Ivana, Csongova Melinda, Glycoconjugate journal . 2016,第4期

机译：显然健康的青少年中晚期糖基化终产物的可溶性受体，可溶性血管黏附蛋白-1 /半氨基脲敏感的胺氧化酶（sVAP-1）与心脏代谢风险标志物之间的相关性：一项横断面研究
3. Plasma soluble receptor for advanced glycation end-products and risk of colorectal adenoma [J] . Li Jiao, Liang Chen, Abeer Alsarraj, International Journal of Molecular Epidemiology and Genetics . 2012,第4期

机译：血浆可溶性受体，用于晚期糖基化终产物和结直肠腺瘤的风险
4. ANTIBODY-FREE LC-MS METHODS FOR LOW TO SUB NG/ML QUANTIFICATION OF THE SOLUBLE RECEPTOR OF ADVANCED GLYCATION END-PRODUCTS (sRAGE) IN SERUM [C] . Frank Klont, Simon D. Pouwels, Marrit Hadderingh, International Mass Spectrometry Conference . 2018

机译：用于低至亚Ng / ml定量的无抗体的LC-MS方法，血清中晚期糖糖末端产物（SRAGE）的可溶性受体的定量
5. Understanding the Role of the Receptor for Advanced Glycation End-Products (RAGE) in Pancreatic Cancer [D] . Swami, Priyanka. 2019

机译：了解受体在胰腺癌中的高级糖化终产物（RAGE）的作用
6. A prospective study of soluble receptor for advanced glycation end-products and colorectal cancer risk in postmenopausal women [O] . Liang Chen, Zhigang Duan, Lesley Tinker, -1

机译：可溶性受体对绝经后妇女晚期糖基化终产物和大肠癌风险的前瞻性研究
7. Advanced Glycation End Products, Soluble Receptor for Advanced Glycation End Products, and Risk of Colorectal Cancer [O] . Jiao, Li, Taylor, Philip R., Weinstein, Stephanie J., 2011

机译：高级糖基化终产物，可溶性受体，用于晚期糖基化终产物和结直肠癌风险

A prospective study of soluble receptor for advanced glycation end-products and colorectal cancer risk in postmenopausal women

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